Homo sapiens
FOXP3
AIID, DIETER, IPEX, PIDX, XPID, JM2
forkhead box P3
GO Process (25)
GO Function (9)
GO Component (3)
Gene Ontology Biological Process
- T cell activation [IDA]
- T cell homeostasis [NAS]
- chromatin remodeling [NAS]
- negative regulation of CREB transcription factor activity [IDA]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of T cell cytokine production [IDA]
- negative regulation of T cell proliferation [IDA]
- negative regulation of activated T cell proliferation [NAS]
- negative regulation of cell proliferation [IDA]
- negative regulation of cytokine biosynthetic process [IDA]
- negative regulation of cytokine secretion [IDA]
- negative regulation of histone deacetylation [IGI]
- negative regulation of immune response [IDA]
- negative regulation of interferon-gamma production [IDA]
- negative regulation of interleukin-10 production [IDA]
- negative regulation of interleukin-2 biosynthetic process [IMP]
- negative regulation of interleukin-2 production [IDA]
- negative regulation of interleukin-4 production [IDA]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of histone acetylation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISS]
- regulation of transcription, DNA-templated [NAS]
- response to virus [IEP]
Gene Ontology Molecular Function- NF-kappaB binding [NAS]
- NFAT protein binding [IPI]
- histone acetyltransferase binding [IPI]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- NF-kappaB binding [NAS]
- NFAT protein binding [IPI]
- histone acetyltransferase binding [IPI]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
Download Curated Data for this Protein
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- Interactors 89
- Interactions 129
- Chemical Interactions 1
- Network
- PTM Sites 1