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Homo sapiens

SIRT6

SIR2L6

sirtuin 6

GO Process (5)

GO Function (7)

GO Component (5)

Gene Ontology Biological Process

histone H3 deacetylation [IDA]

histone H3-K9 modification [IDA]

histone deacetylation [ISS]

protein ADP-ribosylation [ISS, TAS]

regulation of double-strand break repair via homologous recombination [IDA]

Gene Ontology Molecular Function

NAD(P)+-protein-arginine ADP-ribosyltransferase activity [ISS]
NAD+ ADP-ribosyltransferase activity [TAS]
NAD+ binding [ISS]
NAD-dependent histone deacetylase activity [ISS]
NAD-dependent histone deacetylase activity (H3-K9 specific) [IDA]
protein binding [IPI]
zinc ion binding [ISS]

Gene Ontology Cellular Component

intracellular membrane-bounded organelle [IDA]

nuclear telomeric heterochromatin [IDA]

nucleolus [IDA]

nucleoplasm [IDA]

nucleus [IDA, ISS]

CRISPR Database HGNC Alliance of Genome Resources VEGA OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

119603

9606

Interactors 638
Interactions 754
Network
PTM Sites 47