Homo sapiens
NOD2
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
nucleotide-binding oligomerization domain containing 2
GO Process (56)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- JNK cascade [TAS]
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- activation of MAPK activity [TAS]
- activation of MAPK activity involved in innate immune response [ISS]
- cellular response to muramyl dipeptide [IDA]
- cytokine production involved in immune response [IMP]
- defense response [TAS]
- defense response to bacterium [IDA]
- detection of bacterium [IDA]
- detection of biotic stimulus [TAS]
- detection of muramyl dipeptide [IDA]
- innate immune response [IDA, NAS, TAS]
- intracellular signal transduction [IDA]
- maintenance of gastrointestinal epithelium [IMP]
- negative regulation of macrophage apoptotic process [ISS]
- nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]
- nucleotide-binding oligomerization domain containing 2 signaling pathway [IDA]
- nucleotide-binding oligomerization domain containing signaling pathway [TAS]
- positive regulation of B cell activation [IDA]
- positive regulation of ERK1 and ERK2 cascade [ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of JNK cascade [IDA]
- positive regulation of NF-kappaB transcription factor activity [IDA, TAS]
- positive regulation of Notch signaling pathway [ISS]
- positive regulation of dendritic cell antigen processing and presentation [ISS]
- positive regulation of epithelial cell proliferation [ISS]
- positive regulation of gamma-delta T cell activation [ISS]
- positive regulation of interleukin-1 beta production [IMP]
- positive regulation of interleukin-1 beta secretion [IDA]
- positive regulation of interleukin-10 production [ISS]
- positive regulation of interleukin-17 production [IMP]
- positive regulation of interleukin-6 production [IDA]
- positive regulation of nitric-oxide synthase biosynthetic process [ISS]
- positive regulation of oxidoreductase activity [ISS]
- positive regulation of phosphatidylinositol 3-kinase activity [ISS]
- positive regulation of prostaglandin-E synthase activity [ISS]
- positive regulation of prostaglandin-endoperoxide synthase activity [ISS]
- positive regulation of stress-activated MAPK cascade [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of tumor necrosis factor production [IDA, IMP]
- positive regulation of type 2 immune response [IMP]
- protein oligomerization [TAS]
- regulation of inflammatory response [IC]
- response to muramyl dipeptide [IDA]
- stress-activated MAPK cascade [TAS]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
122077
9606
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- Interactors 104
- Interactions 172
- Network
- PTM Sites 13