Homo sapiens

SHARPIN

SIPL1, PSEC0216

SHANK-associated RH domain interactor

GO Process (5)

GO Function (2)

GO Component (5)

Gene Ontology Biological Process

negative regulation of inflammatory response [ISS]

positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]

protein linear polyubiquitination [IDA]

regulation of CD40 signaling pathway [IDA]

regulation of tumor necrosis factor-mediated signaling pathway [IDA]

Gene Ontology Molecular Function

polyubiquitin binding [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

LUBAC complex [IDA]

cytoplasm [IDA]

nucleoplasm [IDA]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

123608

9606

Interactors 188
Interactions 342
Network
PTM Sites 8