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Homo sapiens

DOT1L

DOT1, KMT4

DOT1-like histone H3K79 methyltransferase

GO Process (3)

GO Function (3)

GO Component (0)

Gene Ontology Biological Process

histone lysine methylation [IDA]

regulation of JAK-STAT cascade [IDA]

regulation of transcription regulatory region DNA binding [IMP]

Gene Ontology Molecular Function

histone-lysine N-methyltransferase activity [IDA]
protein binding [IPI]
transcription factor binding [IPI]

CRISPR Database VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

124082

9606

Interactors 812
Interactions 885
Network
PTM Sites 18

Result Summary

DOT1L

Gene Ontology Biological Process

Gene Ontology Molecular Function

histone-lysine N-methyltransferase activity [IDA]protein binding [IPI]transcription factor binding [IPI]

histone-lysine N-methyltransferase activity [IDA]
protein binding [IPI]
transcription factor binding [IPI]