Homo sapiens

EGLN3

HIFP4H3, HIFPH3, PHD3

egl-9 family hypoxia-inducible factor 3

GO Process (9)

GO Function (3)

GO Component (4)

Gene Ontology Biological Process

activation of cysteine-type endopeptidase activity involved in apoptotic process [IEP]

apoptotic process [IEP]

cellular response to hypoxia [TAS]

peptidyl-proline hydroxylation to 4-hydroxy-L-proline [IDA]

protein hydroxylation [IDA]

regulation of cell proliferation [IEP]

regulation of neuron apoptotic process [ISS]

regulation of transcription from RNA polymerase II promoter in response to hypoxia [TAS]

response to hypoxia [IEP]

Gene Ontology Molecular Function

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IDA]
peptidyl-proline 4-dioxygenase activity [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

nucleoplasm [TAS]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

125185

9606

Interactors 1,296
Interactions 1,364
Chemical Interactions 2
Network
PTM Sites 8