Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme.
Yeast Rox3 protein, implicated by genetic evidence in both negative and positive transcriptional regulation, is identified as a mediator subunit by peptide sequence determination and is shown to copurify and co-immunoprecipitate with RNA polymerase II holoenzyme.
Mesh Terms:
Amino Acid Sequence, Fungal Proteins, Gene Expression Regulation, Fungal, Macromolecular Substances, Mediator Complex, Molecular Sequence Data, Precipitin Tests, RNA Polymerase II, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription Factors
Amino Acid Sequence, Fungal Proteins, Gene Expression Regulation, Fungal, Macromolecular Substances, Mediator Complex, Molecular Sequence Data, Precipitin Tests, RNA Polymerase II, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription Factors
J. Biol. Chem.
Date: Jan. 03, 1997
PubMed ID: 8995225
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