Three-dimensional structure of a COPII prebudding complex.

The coat protein complex II (COPII) catalyzes transport vesicle formation from the endoplasmic reticulum. Crystallographic analysis of a Sec23/24-Sar1 prebudding complex of COPII now provides a molecular view of this GTPase-directed coat assembly mechanism.
Mesh Terms:
COP-Coated Vesicles, GTPase-Activating Proteins, Membrane Proteins, Monomeric GTP-Binding Proteins, Nuclear Pore Complex Proteins, Protein Binding, Protein Conformation, Saccharomyces cerevisiae Proteins, Vesicular Transport Proteins
Dev. Cell
Date: Oct. 01, 2002
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