Increase of external osmolarity reduces morphogenetic defects and accumulation of chitin in a gas1 mutant of Saccharomyces cerevisiae.

We have performed a physiological analysis of the effects of high-osmolarity media on gas1Delta cells. The reductions in the duplication time, number of pluribudded cells, hypersensitivity to Calcofluor and sodium dodecyl sulfate, and chitin level indicate a partial suppression of the mutant phenotype. GAS1 deletion was found to be lethal ...
in the absence of the Bck1 and Slt2 (Mpk1) proteins of the cell integrity pathway.
Mesh Terms:
Chitin, Membrane Glycoproteins, Mitogen-Activated Protein Kinase Kinases, Osmolar Concentration, Protein Kinases, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Sodium Dodecyl Sulfate
J. Bacteriol.
Date: Feb. 01, 2000
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