A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation.

The protein encoded by SAC6, a gene that can mutate to suppress a temperature-sensitive defect in the yeast actin gene, has been identified as a 67-kilodalton actin-binding protein (ABP 67) that associates with all identifiable actin structures. This finding demonstrates the in vivo functional importance of the actin-ABP 67 interaction ...
previously established in vitro and illustrates the use of suppressor analysis to identify physically interacting proteins.
Mesh Terms:
Actins, Genes, Genes, Fungal, Microfilament Proteins, Mutation, Restriction Mapping, Saccharomyces cerevisiae, Suppression, Genetic
Science
Date: Jan. 13, 1989
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