Bambuterol, a bronchodilator prodrug with sustained action, enhances delivery of active drug to the lung.

As exemplified with bambuterol, a bronchodilator prodrug with sustained action, increased therapeutic selectivity can be obtained as a result of altered tissue distribution and pharmacokinetics rather than of increased beta 2-adrenoceptor selectivity.
Mesh Terms:
Animals, Asthma, Bronchodilator Agents, Guinea Pigs, Humans, In Vitro Techniques, Lung, Prodrugs, Terbutaline, Tissue Distribution
Agents Actions Suppl.
Date: Jan. 01, 1988
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