Strigolactone/MAX2-induced degradation of brassinosteroid transcriptional effector BES1 regulates shoot branching.
Strigolactones (SLs), a class of the most recently identified terpenoid phytohormones, play essential roles in plant development, specifically in suppressing shoot branching. MAX2, a subunit of an SCF E3 ligase and a positive regulator that inhibits shoot branching, is likely a key SL signaling component. Here, we provide genetic and ... biochemical evidence to demonstrate that BES1 interacts with MAX2 and acts as its substrate to regulate SL-responsive gene expression. Additional AtD14, a putative receptor of SLs, can promote BES1 degradation. Knockdown of BES1 and its homologs dramatically suppressed the branching phenotype of max2-1 mutant. These results portray an SL signaling cascade from the putative receptor to downstream transcription factors. In addition, we demonstrate that the SL and brassinosteroid (BR) signaling pathways distinctly regulate the same transcription factor, BES1, to control specific developmental processes.
Mesh Terms:
Arabidopsis, Arabidopsis Proteins, Brassinosteroids, Carrier Proteins, Fluorescence, Gene Expression Regulation, Plant, Image Processing, Computer-Assisted, Nuclear Proteins, Phenotype, Plant Growth Regulators, Plant Shoots, Proteolysis, Signal Transduction, Two-Hybrid System Techniques, Ubiquitin, Ubiquitination
Arabidopsis, Arabidopsis Proteins, Brassinosteroids, Carrier Proteins, Fluorescence, Gene Expression Regulation, Plant, Image Processing, Computer-Assisted, Nuclear Proteins, Phenotype, Plant Growth Regulators, Plant Shoots, Proteolysis, Signal Transduction, Two-Hybrid System Techniques, Ubiquitin, Ubiquitination
Dev. Cell
Date: Dec. 23, 2013
PubMed ID: 24369836
View in: Pubmed Google Scholar
Download Curated Data For This Publication
185581
Switch View:
- Interactions 10