Sequence, mapping and disruption of CCC1, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants.

We have isolated, sequenced, mapped and disrupted a novel gene, CCC1, from Saccharomyces cerevisiae. This gene displays non-allelic complementation of the Ca(2+)-sensitive phenotype conferred by the csg1 mutation. The ability of this gene, in two copies per cell, to reverse the csg1 defect suggests it may have a role in ...
regulating Ca2+ homeostasis. The sequence of CCC1 indicates that it encodes a 322 amino acid, membrane-associated protein. The CCC1 gene is located on the right arm of chromosome XII.
Mesh Terms:
Amino Acid Sequence, Base Sequence, Calcium, Cation Transport Proteins, Chromosome Mapping, Chromosomes, Fungal, Fungal Proteins, Genes, Fungal, Genetic Complementation Test, Molecular Sequence Data, Phenotype, Protein Structure, Tertiary, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins
Yeast
Date: Apr. 01, 1994
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