Mus musculus
ACVR1
ALK2, ActR-I, ActRIA, Acvr, Acvrlk2, Alk-2, Alk8, D330013D15Rik, SKR1, Tsk7L, RP23-100B18.4
activin A receptor, type 1
GO Process (38)
GO Function (11)
GO Component (3)
Gene Ontology Biological Process
- BMP signaling pathway [ISO]
- G1/S transition of mitotic cell cycle [ISO]
- activin receptor signaling pathway [IDA, ISO]
- atrial septum primum morphogenesis [ISO]
- cardiac muscle cell fate commitment [ISO]
- determination of left/right symmetry [IMP]
- embryo development [IMP]
- embryonic heart tube morphogenesis [ISO]
- endocardial cushion cell fate commitment [ISO]
- gastrulation [IMP]
- gastrulation with mouth forming second [IMP]
- germ cell development [IMP]
- heart development [IMP]
- in utero embryonic development [IMP]
- intracellular signal transduction [ISO]
- mesoderm development [IMP]
- mesoderm formation [IMP]
- mitral valve morphogenesis [ISO]
- negative regulation of activin receptor signaling pathway [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- negative regulation of signal transduction [ISO]
- neural crest cell migration [IMP]
- pathway-restricted SMAD protein phosphorylation [ISO]
- patterning of blood vessels [IMP]
- peptidyl-threonine phosphorylation [ISO]
- pharyngeal system development [IMP]
- positive regulation of bone mineralization [ISO]
- positive regulation of determination of dorsal identity [ISO]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein phosphorylation [IDA, ISO]
- regulation of ossification [ISO]
- signal transduction by phosphorylation [ISO]
- smooth muscle cell differentiation [IMP]
- transforming growth factor beta receptor signaling pathway [IDA, ISO, TAS]
- urogenital system development [ISO]
Gene Ontology Molecular Function- ATP binding [ISO]
- SMAD binding [ISO]
- activin binding [IPI, ISO]
- activin receptor activity, type I [IDA, ISO]
- growth factor binding [IDA]
- protein homodimerization activity [ISO]
- protein kinase activity [ISO]
- protein serine/threonine kinase activity [ISO]
- receptor signaling protein serine/threonine kinase activity [ISO]
- transforming growth factor beta binding [IDA, ISO]
- transforming growth factor beta receptor activity, type I [IDA]
- ATP binding [ISO]
- SMAD binding [ISO]
- activin binding [IPI, ISO]
- activin receptor activity, type I [IDA, ISO]
- growth factor binding [IDA]
- protein homodimerization activity [ISO]
- protein kinase activity [ISO]
- protein serine/threonine kinase activity [ISO]
- receptor signaling protein serine/threonine kinase activity [ISO]
- transforming growth factor beta binding [IDA, ISO]
- transforming growth factor beta receptor activity, type I [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
197953
10090
Switch View:
- Interactors 3
- Interactions 3
- Network
- PTM Sites 18