Mus musculus
ADAM17
CD156b, Tace
a disintegrin and metallopeptidase domain 17
GO Process (31)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
- B cell differentiation [IMP]
- Notch receptor processing [ISO]
- PMA-inducible membrane protein ectodomain proteolysis [IDA, ISO]
- T cell differentiation in thymus [IMP]
- cell adhesion [ISO]
- cell adhesion mediated by integrin [ISO]
- cell motility [IMP]
- epidermal growth factor receptor signaling pathway [ISO]
- epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway [ISO]
- germinal center formation [IMP]
- membrane protein ectodomain proteolysis [IMP, ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of interleukin-8 production [ISO]
- negative regulation of transforming growth factor beta receptor signaling pathway [ISO]
- positive regulation of T cell chemotaxis [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cellular component movement [IMP]
- positive regulation of chemokine production [ISO]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [ISO]
- positive regulation of epidermal growth factor-activated receptor activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of transforming growth factor beta receptor signaling pathway [IMP]
- proteolysis [ISO]
- regulation of mast cell apoptotic process [IMP]
- response to drug [IMP]
- response to high density lipoprotein particle [ISO]
- response to hypoxia [ISO]
- response to lipopolysaccharide [ISO]
- spleen development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
197964
10090
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- Interactors 4
- Interactions 4
- Network
- PTM Sites 3