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Result Summary

Mus musculus

ALOX8

15-LOX-2, 15-LOX-B, 8-LOX, 8S-LOX, Alox15b, RP23-26L6.5
arachidonate 8-lipoxygenase
GO Process (12)
GO Function (5)
GO Component (8)

Gene Ontology Biological Process

  • arachidonic acid metabolic process [IDA, ISO]
  • hepoxilin biosynthetic process [ISO]
  • linoleic acid metabolic process [IDA]
  • lipoxygenase pathway [IDA, ISO]
  • negative regulation of cell cycle [ISO]
  • negative regulation of cell proliferation [ISO]
  • negative regulation of growth [ISO]
  • oxidation-reduction process [IDA]
  • positive regulation of chemokine secretion [ISO]
  • positive regulation of keratinocyte differentiation [IMP]
  • positive regulation of macrophage derived foam cell differentiation [ISO]
  • positive regulation of peroxisome proliferator activated receptor signaling pathway [IMP]

Gene Ontology Molecular Function

  • arachidonate 15-lipoxygenase activity [ISO]
  • arachidonate 8(S)-lipoxygenase activity [IDA]
  • calcium ion binding [ISO]
  • iron ion binding [ISO]
  • linoleate 13S-lipoxygenase activity [ISO]

Gene Ontology Cellular Component

  • cytoplasm [ISO]
  • cytoskeleton [ISO]
  • cytosol [ISO]
  • extracellular vesicular exosome [ISO]
  • extrinsic component of membrane [ISO]
  • intracellular [ISO]
  • membrane [ISO]
  • plasma membrane [ISO]
CRISPR Database MGI Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl
198075
10090

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