Mus musculus
APEX1
APE, Apex, HAP1, Ref-1
apurinic/apyrimidinic endonuclease 1
GO Process (15)
GO Function (14)
GO Component (9)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IBA, ISO]
- DNA catabolic process, exonucleolytic [IBA]
- DNA demethylation [ISO]
- DNA repair [ISO]
- RNA phosphodiester bond hydrolysis, endonucleolytic [ISO]
- aging [ISO]
- base-excision repair [IBA]
- cell redox homeostasis [IDA]
- cellular response to hydrogen peroxide [ISO]
- negative regulation of smooth muscle cell migration [ISO]
- oxidation-reduction process [ISO]
- positive regulation of DNA repair [ISO]
- positive regulation of G1/S transition of mitotic cell cycle [ISO]
- regulation of mRNA stability [ISO]
- regulation of nucleic acid-templated transcription [ISO]
Gene Ontology Molecular Function- 3'-5' exonuclease activity [ISO]
- DNA binding [ISO]
- DNA-(apurinic or apyrimidinic site) lyase activity [IBA, ISO]
- NF-kappaB binding [ISO]
- chromatin DNA binding [ISO]
- damaged DNA binding [ISO]
- double-stranded DNA 3'-5' exodeoxyribonuclease activity [IBA]
- endoribonuclease activity [ISO]
- metal ion binding [ISO]
- oxidoreductase activity [ISO]
- poly(A) RNA binding [ISO]
- protein complex binding [ISO]
- site-specific endodeoxyribonuclease activity, specific for altered base [ISO]
- transcription coactivator activity [ISO]
- 3'-5' exonuclease activity [ISO]
- DNA binding [ISO]
- DNA-(apurinic or apyrimidinic site) lyase activity [IBA, ISO]
- NF-kappaB binding [ISO]
- chromatin DNA binding [ISO]
- damaged DNA binding [ISO]
- double-stranded DNA 3'-5' exodeoxyribonuclease activity [IBA]
- endoribonuclease activity [ISO]
- metal ion binding [ISO]
- oxidoreductase activity [ISO]
- poly(A) RNA binding [ISO]
- protein complex binding [ISO]
- site-specific endodeoxyribonuclease activity, specific for altered base [ISO]
- transcription coactivator activity [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
198145
10090
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- Interactors 19
- Interactions 20
- Network
- PTM Sites 1