Mus musculus
BMP2
AI467020, Bmp2a, RP23-384M14.3
bone morphogenetic protein 2
GO Process (86)
GO Function (12)
GO Component (5)
Gene Ontology Biological Process
- BMP signaling pathway [IDA, IGI, ISO]
- BMP signaling pathway involved in heart induction [ISO]
- Notch signaling pathway [IMP]
- SMAD protein signal transduction [IBA, ISO]
- activation of MAPK activity [ISO]
- atrioventricular valve morphogenesis [IMP]
- bone mineralization [IDA, IGI]
- bone mineralization involved in bone maturation [ISO]
- branching involved in ureteric bud morphogenesis [IGI]
- cardiac epithelial to mesenchymal transition [ISO]
- cardiac muscle cell differentiation [ISO]
- cardiac muscle tissue morphogenesis [IMP]
- cardiocyte differentiation [ISO]
- cell fate commitment [IMP]
- cellular response to BMP stimulus [ISO]
- cellular response to growth factor stimulus [IDA]
- cellular response to organic cyclic compound [IDA]
- chondrocyte differentiation [ISO]
- corticotropin hormone secreting cell differentiation [IDA]
- embryo development [IMP]
- embryonic heart tube anterior/posterior pattern specification [IMP]
- endocardial cushion morphogenesis [IMP]
- epithelial to mesenchymal transition [ISO]
- heart development [IMP]
- in utero embryonic development [IMP]
- inner ear development [IDA]
- mesenchymal cell differentiation [ISO]
- mesenchymal cell proliferation involved in ureteric bud development [IMP]
- mesenchyme development [ISO]
- negative regulation of Wnt signaling pathway involved in heart development [ISO]
- negative regulation of aldosterone biosynthetic process [ISO]
- negative regulation of calcium-independent cell-cell adhesion [ISO]
- negative regulation of cardiac muscle cell differentiation [ISO]
- negative regulation of cell cycle [ISO]
- negative regulation of cell proliferation [IGI, ISO]
- negative regulation of cortisol biosynthetic process [ISO]
- negative regulation of gene expression [IDA]
- negative regulation of insulin-like growth factor receptor signaling pathway [ISO]
- negative regulation of steroid biosynthetic process [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- negative regulation of transcription, DNA-templated [ISO]
- odontogenesis of dentin-containing tooth [IDA]
- organ morphogenesis [IMP]
- osteoblast differentiation [IDA, IGI, ISO]
- oxidation-reduction process [IDA]
- pathway-restricted SMAD protein phosphorylation [ISO]
- pericardium development [IMP]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of Wnt signaling pathway [IDA]
- positive regulation of Wnt signaling pathway by BMP signaling pathway [IDA]
- positive regulation of apoptotic process [ISO]
- positive regulation of astrocyte differentiation [IDA, IGI]
- positive regulation of bone mineralization [ISO]
- positive regulation of cartilage development [IDA, ISO]
- positive regulation of cell differentiation [IDA]
- positive regulation of cell migration [IMP]
- positive regulation of endothelial cell proliferation [ISO]
- positive regulation of epithelial to mesenchymal transition [IMP, ISO]
- positive regulation of fat cell differentiation [IDA]
- positive regulation of gene expression [IDA, ISO]
- positive regulation of neurogenesis [ISO]
- positive regulation of neuron differentiation [IDA]
- positive regulation of odontogenesis [IDA]
- positive regulation of ossification [IDA, ISO]
- positive regulation of osteoblast differentiation [IDA, IMP, ISO]
- positive regulation of osteoblast proliferation [IMP]
- positive regulation of p38MAPK cascade [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IBA, ISO]
- positive regulation of phosphatase activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein destabilization [IDA, IGI]
- protein phosphorylation [ISO]
- proteoglycan metabolic process [IGI]
- regulation of MAPK cascade [IBA]
- regulation of apoptotic process [IBA]
- regulation of odontogenesis of dentin-containing tooth [IGI]
- regulation of transcription, DNA-templated [ISO]
- response to hypoxia [IMP]
- telencephalon development [ISO]
- telencephalon regionalization [IGI]
- thyroid-stimulating hormone-secreting cell differentiation [IDA]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function- BMP receptor binding [IBA, ISO]
- SMAD binding [ISO]
- cytokine activity [TAS]
- growth factor activity [ISO]
- phosphatase activator activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- retinol dehydrogenase activity [IDA]
- transforming growth factor beta receptor binding [IBA]
- BMP receptor binding [IBA, ISO]
- SMAD binding [ISO]
- cytokine activity [TAS]
- growth factor activity [ISO]
- phosphatase activator activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- retinol dehydrogenase activity [IDA]
- transforming growth factor beta receptor binding [IBA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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