Mus musculus
CDKN1A
CAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF
cyclin-dependent kinase inhibitor 1A (P21)
GO Process (29)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [ISO]
- G1/S transition of mitotic cell cycle [ISO]
- G2/M transition of mitotic cell cycle [ISO]
- cell cycle arrest [IDA, ISO]
- cellular response to DNA damage stimulus [IMP, ISO]
- cellular response to extracellular stimulus [ISO]
- cellular response to ionizing radiation [ISO]
- cellular senescence [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- mitotic cell cycle arrest [IDA]
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP, ISO]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
- negative regulation of gene expression [IMP]
- negative regulation of phosphorylation [ISO]
- positive regulation of B cell proliferation [IGI]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of programmed cell death [IMP]
- positive regulation of protein kinase activity [ISO]
- positive regulation of reactive oxygen species metabolic process [ISO]
- protein phosphorylation [ISO]
- regulation of DNA biosynthetic process [IMP]
- regulation of cell cycle [IDA]
- regulation of cyclin-dependent protein serine/threonine kinase activity [IMP]
- regulation of mitotic cell cycle [IMP]
- regulation of protein import into nucleus, translocation [IMP]
- response to UV [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
198651
10090
Switch View:
- Interactors 17
- Interactions 35
- Network
- PTM Sites 1