Mus musculus
DDIT3
CHOP-10, CHOP10, chop, gadd153
DNA-damage inducible transcript 3
GO Process (28)
GO Function (8)
GO Component (8)
Gene Ontology Biological Process
- ER overload response [IMP, ISO]
- apoptotic process [IMP]
- blood vessel maturation [IMP]
- cell redox homeostasis [ISO]
- endoplasmic reticulum unfolded protein response [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IMP, ISO]
- mRNA transcription from RNA polymerase II promoter [ISO]
- negative regulation of CREB transcription factor activity [ISO]
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of determination of dorsal identity [IDA, ISO]
- negative regulation of fat cell differentiation [IGI]
- negative regulation of myoblast differentiation [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [IDA, IMP, ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of interleukin-8 production [ISO]
- positive regulation of neuron apoptotic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- regulation of transcription involved in anterior/posterior axis specification [IDA]
- regulation of transcription, DNA-templated [IMP, ISO]
- release of sequestered calcium ion into cytosol [IMP]
- response to endoplasmic reticulum stress [IDA, ISO]
- response to starvation [IDA]
- response to unfolded protein [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IMP, ISO]
- transcription factor binding [ISO]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IMP, ISO]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
- CHOP-C/EBP complex [ISO]
- cell [IMP]
- cytoplasm [ISO]
- cytosol [IMP]
- intracellular [IMP]
- late endosome [IDA]
- nucleoplasm [ISO]
- nucleus [IC, IDA, ISO]
Download Curated Data for this Protein
199078
10090
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- Interactors 5
- Interactions 7
- Network