Mus musculus
DRD2
D2R, Drd-2
dopamine receptor D2
GO Process (88)
GO Function (10)
GO Component (16)
Gene Ontology Biological Process
- G-protein coupled receptor internalization [ISO]
- G-protein coupled receptor signaling pathway [IDA]
- Wnt signaling pathway [ISO]
- acid secretion [ISO]
- activation of protein kinase activity [ISO]
- adenohypophysis development [IMP]
- adenylate cyclase-inhibiting dopamine receptor signaling pathway [IDA, IGI, IMP, ISO]
- adenylate cyclase-modulating G-protein coupled receptor signaling pathway [ISO]
- adult behavior [IMP]
- adult walking behavior [IMP]
- arachidonic acid secretion [ISO]
- associative learning [IMP]
- auditory behavior [ISO]
- axonogenesis [IMP]
- behavioral response to cocaine [IMP]
- behavioral response to ethanol [IMP]
- branching morphogenesis of a nerve [IMP]
- cerebral cortex GABAergic interneuron migration [IMP]
- circadian regulation of gene expression [IMP]
- dopamine metabolic process [IMP]
- dopamine receptor signaling pathway [IGI, ISO]
- feeding behavior [IGI]
- forebrain development [ISO]
- grooming behavior [IMP]
- intracellular signal transduction [ISO]
- locomotory behavior [IGI, IMP, ISO]
- long-term memory [ISO]
- negative regulation of adenylate cyclase activity [ISO]
- negative regulation of blood pressure [IMP]
- negative regulation of cell migration [IMP]
- negative regulation of cell proliferation [IGI, IMP]
- negative regulation of circadian sleep/wake cycle, sleep [ISO]
- negative regulation of cytosolic calcium ion concentration [ISO]
- negative regulation of dopamine receptor signaling pathway [IGI, IMP]
- negative regulation of dopamine secretion [ISO]
- negative regulation of insulin secretion [ISO]
- negative regulation of protein kinase B signaling [IMP]
- negative regulation of protein secretion [ISO]
- negative regulation of synaptic transmission, glutamatergic [IMP]
- negative regulation of voltage-gated calcium channel activity [ISO]
- neurological system process involved in regulation of systemic arterial blood pressure [IMP]
- neuron-neuron synaptic transmission [IMP]
- peristalsis [IGI, IMP]
- phosphatidylinositol metabolic process [ISO]
- phospholipase C-activating dopamine receptor signaling pathway [IDA, IGI, ISO]
- pigmentation [IMP]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of G-protein coupled receptor protein signaling pathway [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [ISO]
- positive regulation of dopamine uptake involved in synaptic transmission [IMP]
- positive regulation of growth hormone secretion [IMP]
- positive regulation of long-term synaptic potentiation [ISO]
- positive regulation of multicellular organism growth [IMP]
- positive regulation of neuroblast proliferation [IDA]
- positive regulation of receptor internalization [ISO]
- positive regulation of renal sodium excretion [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of urine volume [IMP]
- prepulse inhibition [IMP]
- protein localization [IMP]
- regulation of MAPK cascade [ISO]
- regulation of cAMP metabolic process [ISO]
- regulation of dopamine secretion [IMP]
- regulation of dopamine uptake involved in synaptic transmission [IMP]
- regulation of heart rate [IMP]
- regulation of locomotion involved in locomotory behavior [ISO]
- regulation of long-term neuronal synaptic plasticity [IMP]
- regulation of phosphoprotein phosphatase activity [ISO]
- regulation of potassium ion transport [IMP, ISO]
- regulation of sodium ion transport [IMP]
- regulation of synapse structural plasticity [ISO]
- regulation of synaptic transmission [IMP, ISO]
- regulation of synaptic transmission, GABAergic [IGI, IMP]
- release of sequestered calcium ion into cytosol [ISO]
- response to amphetamine [IGI, IMP]
- response to cocaine [IDA, IMP]
- response to drug [IDA, IMP, ISO]
- response to histamine [ISO]
- response to hypoxia [ISO]
- response to light stimulus [IMP]
- response to morphine [IMP]
- sensory perception of smell [IMP]
- startle response [IMP]
- synaptic transmission [IDA]
- synaptic transmission, dopaminergic [ISO]
- temperature homeostasis [IMP]
- visual learning [IMP]
Gene Ontology Molecular Function- G-protein coupled receptor activity [IDA]
- dopamine binding [IDA, ISO]
- dopamine neurotransmitter receptor activity [IDA, ISO]
- dopamine neurotransmitter receptor activity, coupled via Gi/Go [IDA, IMP, ISO]
- drug binding [ISO]
- identical protein binding [ISO]
- ionotropic glutamate receptor binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- G-protein coupled receptor activity [IDA]
- dopamine binding [IDA, ISO]
- dopamine neurotransmitter receptor activity [IDA, ISO]
- dopamine neurotransmitter receptor activity, coupled via Gi/Go [IDA, IMP, ISO]
- drug binding [ISO]
- identical protein binding [ISO]
- ionotropic glutamate receptor binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
Gene Ontology Cellular Component
- acrosomal vesicle [ISO]
- axon [IDA, ISO]
- axon terminus [ISO]
- cytoplasmic vesicle [ISO]
- cytosol [ISO]
- dendrite [IDA, ISO]
- dendritic spine [ISO]
- endocytic vesicle [ISO]
- integral component of plasma membrane [ISO]
- lateral plasma membrane [ISO]
- membrane [IDA, ISO]
- perikaryon [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- sperm flagellum [ISO]
- synaptic vesicle membrane [ISO]
Download Curated Data for this Protein
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- Interactors 7
- Interactions 12
- Network
- PTM Sites 1