Mus musculus
ERBB2
Erbb-2, HER-2, HER2, Neu, c-erbB2, c-neu, mKIAA3023, RP23-355L10.8
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
GO Process (35)
GO Function (13)
GO Component (15)
Gene Ontology Biological Process
- cell surface receptor signaling pathway [ISO]
- estrus [ISO]
- glial cell differentiation [ISO]
- heart development [IMP]
- motor neuron axon guidance [IMP]
- myelination [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of immature T cell proliferation in thymus [IMP]
- nervous system development [IMP]
- neuromuscular junction development [IMP]
- oligodendrocyte differentiation [IMP]
- peptidyl-tyrosine phosphorylation [ISO]
- peripheral nervous system development [IMP, ISO]
- phosphatidylinositol 3-kinase signaling [ISO]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of Ras protein signal transduction [ISO]
- positive regulation of Rho GTPase activity [IMP]
- positive regulation of cell adhesion [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO]
- positive regulation of protein phosphorylation [IMP]
- positive regulation of transcription from RNA polymerase I promoter [ISO]
- positive regulation of transcription from RNA polymerase III promoter [ISO]
- positive regulation of translation [ISO]
- protein autophosphorylation [ISO]
- regulation of ERK1 and ERK2 cascade [ISO]
- regulation of microtubule-based process [ISO]
- response to axon injury [ISO]
- signal transduction [ISO]
- sympathetic nervous system development [ISO]
- transmembrane receptor protein tyrosine kinase signaling pathway [ISO]
- wound healing [ISO]
Gene Ontology Molecular Function- Hsp90 protein binding [ISO]
- RNA polymerase I core binding [ISO]
- glycoprotein binding [ISO]
- growth factor binding [ISO]
- identical protein binding [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein phosphatase binding [ISO]
- protein tyrosine kinase activity [ISO]
- transmembrane receptor protein tyrosine kinase activity [ISO]
- transmembrane signaling receptor activity [ISO]
- ubiquitin protein ligase binding [ISO]
- Hsp90 protein binding [ISO]
- RNA polymerase I core binding [ISO]
- glycoprotein binding [ISO]
- growth factor binding [ISO]
- identical protein binding [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein phosphatase binding [ISO]
- protein tyrosine kinase activity [ISO]
- transmembrane receptor protein tyrosine kinase activity [ISO]
- transmembrane signaling receptor activity [ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
- apical plasma membrane [IDA, ISO]
- basal plasma membrane [ISO]
- basolateral plasma membrane [ISO]
- cytoplasm [IDA, ISO]
- cytoplasmic vesicle [IDA]
- endosome membrane [ISO]
- integral component of membrane [NAS]
- lateral loop [ISO]
- membrane raft [ISO]
- microvillus [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic membrane [ISO]
- receptor complex [ISO]
Download Curated Data for this Protein
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10090
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- Interactors 9
- Interactions 10
- Network
- PTM Sites 1