Mus musculus
PTPN6
70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
protein tyrosine phosphatase, non-receptor type 6
GO Process (29)
GO Function (8)
GO Component (7)
Gene Ontology Biological Process
- B cell receptor signaling pathway [IMP]
- abortive mitotic cell cycle [IMP]
- cell differentiation [ISO]
- cell proliferation [ISO]
- cytokine-mediated signaling pathway [TAS]
- hematopoietic progenitor cell differentiation [IMP]
- intracellular signal transduction [IDA]
- megakaryocyte development [IMP]
- natural killer cell mediated cytotoxicity [IMP]
- negative regulation of B cell receptor signaling pathway [IGI]
- negative regulation of MAP kinase activity [IMP]
- negative regulation of MAPK cascade [IMP]
- negative regulation of T cell proliferation [IMP]
- negative regulation of T cell receptor signaling pathway [IMP]
- negative regulation of humoral immune response mediated by circulating immunoglobulin [IMP]
- negative regulation of peptidyl-tyrosine phosphorylation [IMP, ISO]
- peptidyl-tyrosine dephosphorylation [IDA, ISO]
- peptidyl-tyrosine phosphorylation [ISO]
- platelet aggregation [IMP]
- platelet formation [IGI]
- positive regulation of cell adhesion mediated by integrin [IMP]
- positive regulation of cell proliferation [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO]
- protein dephosphorylation [IDA, IMP, ISO]
- regulation of B cell differentiation [IMP]
- regulation of ERK1 and ERK2 cascade [ISO]
- regulation of G1/S transition of mitotic cell cycle [ISO]
- regulation of release of sequestered calcium ion into cytosol [IGI]
- signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
200256
10090
Switch View:
- Interactors 23
- Interactions 27
- Network