Mus musculus
HES1
Hry, bHLHb39
hairy and enhancer of split 1 (Drosophila)
GO Process (74)
GO Function (11)
GO Component (4)
Gene Ontology Biological Process
- Notch signaling pathway [ISO, NAS, TAS]
- STAT protein import into nucleus [IDA]
- adenohypophysis development [IMP]
- aorta morphogenesis [IMP]
- artery morphogenesis [IMP]
- ascending aorta morphogenesis [IMP]
- auditory receptor cell differentiation [IMP]
- auditory receptor cell fate determination [IMP]
- cardiac neural crest cell development involved in outflow tract morphogenesis [IMP]
- cell adhesion [IGI]
- cell fate commitment [IMP]
- cell maturation [IGI]
- cell migration [IGI]
- cell morphogenesis involved in neuron differentiation [IGI]
- cochlea development [IGI, IMP]
- common bile duct development [IMP]
- embryonic heart tube morphogenesis [IMP]
- forebrain radial glial cell differentiation [ISO]
- hindbrain morphogenesis [IGI]
- in utero embryonic development [IGI]
- labyrinthine layer blood vessel development [IMP]
- lateral inhibition [IMP]
- liver development [IMP]
- lung development [IMP]
- midbrain development [IGI]
- midbrain-hindbrain boundary morphogenesis [IGI]
- negative regulation of auditory receptor cell differentiation [IMP]
- negative regulation of cell differentiation [IMP]
- negative regulation of forebrain neuron differentiation [ISO]
- negative regulation of glial cell proliferation [IDA]
- negative regulation of inner ear receptor cell differentiation [IMP]
- negative regulation of neuron differentiation [IGI, IMP]
- negative regulation of oligodendrocyte differentiation [IDA]
- negative regulation of pancreatic A cell differentiation [IMP]
- negative regulation of pro-B cell differentiation [ISO]
- negative regulation of stem cell differentiation [ISO]
- negative regulation of stomach neuroendocrine cell differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- negative regulation of transcription, DNA-templated [IMP, ISO]
- neural tube development [IGI]
- neuronal stem cell maintenance [IMP, ISO]
- oculomotor nerve development [IGI]
- outflow tract morphogenesis [IMP]
- pancreas development [IMP]
- pattern specification process [IGI, IMP]
- pharyngeal arch artery morphogenesis [IMP]
- pituitary gland development [IGI, IMP]
- positive regulation of BMP signaling pathway [IGI]
- positive regulation of DNA binding [IDA]
- positive regulation of JAK-STAT cascade [IDA]
- positive regulation of Notch signaling pathway [IMP]
- positive regulation of T cell proliferation [IMP]
- positive regulation of astrocyte differentiation [IDA]
- positive regulation of cell proliferation [IMP]
- positive regulation of mitotic cell cycle, embryonic [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IGI, IMP]
- positive regulation of transcription, DNA-templated [IMP]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IDA]
- protein complex assembly [IDA]
- regulation of fat cell differentiation [IMP]
- regulation of neurogenesis [IGI]
- regulation of secondary heart field cardioblast proliferation [IMP]
- regulation of timing of cell differentiation [IMP]
- regulation of timing of neuron differentiation [IGI, IMP]
- regulation of transcription from RNA polymerase II promoter [IGI]
- smoothened signaling pathway [IDA]
- somatic stem cell maintenance [IMP]
- telencephalon development [IGI, IMP]
- thymus development [IMP]
- transcription from RNA polymerase II promoter [IDA]
- trochlear nerve development [IGI]
- vascular smooth muscle cell development [IMP]
- ventricular septum development [IMP]
- ventricular septum morphogenesis [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- N-box binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- chaperone binding [IDA]
- histone deacetylase binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [NAS]
- DNA binding [IDA]
- N-box binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- chaperone binding [IDA]
- histone deacetylase binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [NAS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
200275
10090
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- Interactors 8
- Interactions 9
- Network