Mus musculus
HIPK2
1110014O20Rik, B230339E18Rik, Stank
homeodomain interacting protein kinase 2
GO Process (32)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [ISO]
- SMAD protein signal transduction [ISO]
- adult locomotory behavior [IMP]
- adult walking behavior [IMP]
- anterior/posterior pattern specification [IGI]
- embryonic camera-type eye morphogenesis [IMP]
- embryonic retina morphogenesis in camera-type eye [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IGI]
- iris morphogenesis [IMP]
- lens induction in camera-type eye [IMP]
- negative regulation of BMP signaling pathway [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of nucleic acid-templated transcription [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- neuron differentiation [IMP]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of DNA binding [IDA]
- positive regulation of JNK cascade [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of cell proliferation [IGI]
- positive regulation of protein binding [IDA]
- positive regulation of protein phosphorylation [IGI]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IGI, IMP]
- positive regulation of transcription, DNA-templated [ISO]
- positive regulation of transforming growth factor beta receptor signaling pathway [ISO]
- protein phosphorylation [IDA, ISA, ISO]
- retina layer formation [IMP]
- smoothened signaling pathway [IGI]
- transforming growth factor beta receptor signaling pathway [IMP]
- voluntary musculoskeletal movement [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II transcription coactivator activity [IMP]
- SMAD binding [ISO]
- protein binding [IPI]
- protein kinase activity [IDA, ISO]
- protein serine/threonine kinase activity [IDA, ISA]
- transcription corepressor activity [IDA, ISO]
- virion binding [ISO]
- DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II transcription coactivator activity [IMP]
- SMAD binding [ISO]
- protein binding [IPI]
- protein kinase activity [IDA, ISO]
- protein serine/threonine kinase activity [IDA, ISA]
- transcription corepressor activity [IDA, ISO]
- virion binding [ISO]
Gene Ontology Cellular Component
- PML body [ISO, TAS]
- cytoplasm [IDA]
- intracellular [IGI]
- nuclear body [ISO]
- nucleus [IDA, ISO]
- protein complex [IMP]
Download Curated Data for this Protein
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10090
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- Interactors 11
- Interactions 15
- Network