Mus musculus
IL12B
Il-12b, Il-12p40, Il12p40, p40, RP23-388G23.1
interleukin 12b
GO Process (44)
GO Function (9)
GO Component (4)
Gene Ontology Biological Process
- T-helper cell differentiation [ISO]
- cell cycle arrest [ISO]
- cell migration [ISO]
- cell surface receptor signaling pathway [IDA]
- cellular response to interferon-gamma [IDA]
- cellular response to lipopolysaccharide [IDA]
- defense response to Gram-negative bacterium [ISO]
- defense response to protozoan [IGI, IMP]
- defense response to virus [IDA]
- natural killer cell activation [ISO]
- natural killer cell activation involved in immune response [ISO]
- negative regulation of growth of symbiont in host [IMP]
- negative regulation of inflammatory response to antigenic stimulus [IMP]
- negative regulation of interleukin-10 production [ISO]
- negative regulation of interleukin-17 production [ISO]
- negative regulation of smooth muscle cell proliferation [ISO]
- positive regulation of NK T cell activation [ISO]
- positive regulation of NK T cell proliferation [ISO]
- positive regulation of T cell mediated cytotoxicity [IDA]
- positive regulation of T cell proliferation [IDA, ISO]
- positive regulation of T-helper 1 type immune response [IDA, ISO]
- positive regulation of activated T cell proliferation [ISO]
- positive regulation of activation of JAK2 kinase activity [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of defense response to virus by host [IDA, ISO]
- positive regulation of granulocyte macrophage colony-stimulating factor production [ISO]
- positive regulation of interferon-gamma production [IGI, IMP, ISO]
- positive regulation of interleukin-10 production [ISO]
- positive regulation of interleukin-12 production [ISO]
- positive regulation of interleukin-17 production [ISO]
- positive regulation of lymphocyte proliferation [ISO]
- positive regulation of mononuclear cell proliferation [ISO]
- positive regulation of natural killer cell activation [ISO]
- positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [ISO]
- positive regulation of natural killer cell proliferation [ISO]
- positive regulation of osteoclast differentiation [ISO]
- positive regulation of smooth muscle cell apoptotic process [ISO]
- positive regulation of tumor necrosis factor production [ISO]
- positive regulation of tyrosine phosphorylation of Stat3 protein [ISO]
- positive regulation of tyrosine phosphorylation of Stat4 protein [ISO]
- positive regulation of tyrosine phosphorylation of Stat5 protein [ISO]
- regulation of tyrosine phosphorylation of Stat1 protein [ISO]
- response to UV-B [ISO]
- sensory perception of pain [ISO]
Gene Ontology Molecular Function- cytokine activity [IDA, ISO]
- cytokine receptor binding [IPI]
- growth factor activity [ISO]
- identical protein binding [ISO]
- interleukin-12 alpha subunit binding [IPI, ISO]
- interleukin-23 receptor binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [IDA]
- cytokine activity [IDA, ISO]
- cytokine receptor binding [IPI]
- growth factor activity [ISO]
- identical protein binding [ISO]
- interleukin-12 alpha subunit binding [IPI, ISO]
- interleukin-23 receptor binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
200610
10090