Mus musculus
IRAK1
AA408924, IRAK, IRAK-1, IRAK1-S, Il1rak, Plpk, mPLK, RP23-252M19.7
interleukin-1 receptor-associated kinase 1
GO Process (23)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- JNK cascade [ISO]
- activation of NF-kappaB-inducing kinase activity [ISO]
- cellular response to heat [ISO]
- cytokine-mediated signaling pathway [IDA, ISO]
- interleukin-1-mediated signaling pathway [IDA, ISO]
- lipopolysaccharide-mediated signaling pathway [IDA, ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of cholesterol efflux [IMP]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IBA, ISO]
- positive regulation of JUN kinase activity [IMP]
- positive regulation of MAP kinase activity [IMP]
- positive regulation of NF-kappaB transcription factor activity [IDA, ISO]
- positive regulation of smooth muscle cell proliferation [ISO]
- protein autophosphorylation [IDA, ISO]
- protein oligomerization [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of cytokine-mediated signaling pathway [ISO]
- response to interleukin-1 [ISO]
- response to lipopolysaccharide [IDA, ISO]
- response to peptidoglycan [IDA]
- toll-like receptor 2 signaling pathway [IDA, ISO]
- toll-like receptor 4 signaling pathway [IDA]
Gene Ontology Molecular Function
Download Curated Data for this Protein
200627
10090
Switch View:
- Interactors 27
- Interactions 36
- Network
- PTM Sites 6