Mus musculus
IRF1
AU020929, Irf-1, RP23-303F24.1
interferon regulatory factor 1
GO Process (29)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- CD8-positive, alpha-beta T cell differentiation [IMP]
- I-kappaB kinase/NF-kappaB signaling [ISO]
- apoptotic process [ISO]
- cell cycle arrest [ISO]
- cellular response to interferon-beta [ISO]
- cellular response to interleukin-1 [ISO]
- cellular response to peptide hormone stimulus [ISO]
- cellular response to tumor necrosis factor [ISO]
- defense response to virus [IMP, ISO]
- interferon-gamma-mediated signaling pathway [IMP]
- negative regulation of T-helper 2 cell differentiation [TAS]
- negative regulation of regulatory T cell differentiation [IMP]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- negative regulation of tyrosine phosphorylation of Stat1 protein [ISO]
- positive regulation of T-helper 1 cell differentiation [TAS]
- positive regulation of cell death [ISO]
- positive regulation of interferon-beta production [ISO]
- positive regulation of interleukin-12 biosynthetic process [IDA, IMP]
- positive regulation of natural killer cell differentiation [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISO]
- positive regulation of type I interferon production [IMP]
- regulation of CD8-positive, alpha-beta T cell proliferation [IMP]
- regulation of MyD88-dependent toll-like receptor signaling pathway [IMP]
- regulation of adaptive immune response [TAS]
- regulation of gene expression [IMP]
- regulation of innate immune response [TAS]
- response to growth hormone [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
Download Curated Data for this Protein
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- Interactors 7
- Interactions 11
- Network
- PTM Sites 2