Mus musculus
ISL1
ISL1 transcription factor, LIM/homeodomain
GO Process (55)
GO Function (12)
GO Component (4)
Gene Ontology Biological Process
- atrial septum morphogenesis [IGI]
- cardiac cell fate determination [IMP, ISO]
- cardiac muscle cell myoblast differentiation [IMP]
- cardiac right ventricle morphogenesis [IGI]
- endocardial cushion morphogenesis [IGI]
- heart development [IMP]
- heart morphogenesis [IGI]
- innervation [IMP]
- mesenchymal cell differentiation [IMP]
- negative regulation of canonical Wnt signaling pathway [IGI]
- negative regulation of inflammatory response [IMP]
- negative regulation of intracellular estrogen receptor signaling pathway [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of neuron differentiation [IGI]
- negative regulation of protein homodimerization activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- neural crest cell migration [IGI]
- neuron differentiation [IGI, IMP]
- neuron fate commitment [IGI]
- neuron fate specification [IMP]
- outflow tract morphogenesis [IGI]
- outflow tract septum morphogenesis [IGI]
- pancreas development [IMP]
- peripheral nervous system neuron axonogenesis [IMP]
- peripheral nervous system neuron development [IGI]
- pharyngeal system development [IGI]
- pituitary gland development [IMP]
- positive regulation of DNA binding [IDA]
- positive regulation of angiogenesis [IMP]
- positive regulation of cell proliferation [IDA]
- positive regulation of granulocyte colony-stimulating factor production [IDA]
- positive regulation of granulocyte macrophage colony-stimulating factor production [IDA]
- positive regulation of insulin secretion [ISO]
- positive regulation of interferon-gamma production [IDA]
- positive regulation of interleukin-1 alpha production [IDA]
- positive regulation of interleukin-1 beta production [IDA]
- positive regulation of interleukin-12 production [IDA]
- positive regulation of interleukin-6 production [IDA]
- positive regulation of macrophage colony-stimulating factor production [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of tumor necrosis factor production [IDA]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IDA]
- positive regulation vascular endothelial growth factor production [IDA]
- regulation of gene expression [IMP]
- regulation of secondary heart field cardioblast proliferation [IMP]
- regulation of transcription, DNA-templated [ISO]
- retinal ganglion cell axon guidance [IMP]
- secondary heart field specification [ISO]
- sensory system development [IMP]
- spinal cord motor neuron cell fate specification [IGI]
- spinal cord motor neuron differentiation [IMP]
- transcription from RNA polymerase II promoter [ISO]
- trigeminal nerve development [IMP]
- ventricular cardiac muscle tissue morphogenesis [IGI]
- visceral motor neuron differentiation [IGI]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II transcription coactivator activity [IDA, ISO]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- enhancer sequence-specific DNA binding [ISO]
- estrogen receptor binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II transcription coactivator activity [IDA, ISO]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- enhancer sequence-specific DNA binding [ISO]
- estrogen receptor binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
200812
10090
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- Interactors 8
- Interactions 10
- Network