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Result Summary

Mus musculus

ITGAL

(p180), Cd11a, LFA-1, LFA-1A, Ly-15, Ly-21
integrin alpha L
GO Process (13)
GO Function (4)
GO Component (7)

Gene Ontology Biological Process

  • T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [ISO]
  • activated T cell proliferation [IMP]
  • cell surface receptor signaling pathway [IDA]
  • cell-matrix adhesion [ISO]
  • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [ISO]
  • leukocyte cell-cell adhesion [IDA, IMP, ISO]
  • positive regulation of T cell proliferation [IMP]
  • positive regulation of calcium-mediated signaling [IDA]
  • positive regulation of cell-cell adhesion [IMP]
  • receptor clustering [ISO]
  • regulation of cell-cell adhesion [IDA]
  • signal transduction [ISO]
  • single organismal cell-cell adhesion [ISO]

Gene Ontology Molecular Function

  • ICAM-3 receptor activity [ISO]
  • cell adhesion molecule binding [ISO]
  • protein complex binding [ISO]
  • protein heterodimerization activity [ISO]

Gene Ontology Cellular Component

  • cell surface [ISO]
  • cell-cell junction [IDA]
  • external side of plasma membrane [IDA]
  • extracellular vesicular exosome [ISO]
  • immunological synapse [IDA]
  • integrin alphaL-beta2 complex [ISO]
  • membrane [ISO]
CRISPR Database VEGA MGI Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl
200822
10090

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