Mus musculus
ITGAV
1110004F14Rik, 2610028E01Rik, CD51, D430040G12Rik, RP23-111F12.3
integrin alpha V
GO Process (45)
GO Function (11)
GO Component (18)
Gene Ontology Biological Process
- ERK1 and ERK2 cascade [IDA]
- T cell activation [TAS]
- apolipoprotein A-I-mediated signaling pathway [ISO]
- apoptotic cell clearance [IMP]
- blood vessel development [IMP]
- calcium ion transmembrane transport [ISO]
- cell adhesion [ISO]
- cell growth [ISO]
- cell migration [ISO]
- cell-matrix adhesion [ISO, TAS]
- cell-substrate adhesion [ISO]
- cellular calcium ion homeostasis [ISO]
- detection of molecule of bacterial origin [TAS]
- endodermal cell differentiation [ISO]
- endothelial cell migration [TAS]
- extrinsic apoptotic signaling pathway in absence of ligand [IDA]
- fertilization [NAS]
- focal adhesion assembly [NAS]
- gonad morphogenesis [NAS]
- heterotypic cell-cell adhesion [ISO]
- inflammatory response [TAS]
- integrin-mediated signaling pathway [ISO]
- negative chemotaxis [ISO]
- negative regulation of entry of bacterium into host cell [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- negative regulation of lipid storage [ISO]
- negative regulation of lipid transport [ISO]
- negative regulation of lipoprotein metabolic process [ISO]
- negative regulation of low-density lipoprotein particle receptor biosynthetic process [ISO]
- negative regulation of macrophage derived foam cell differentiation [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of cell migration [IMP]
- positive regulation of cell proliferation [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of osteoblast proliferation [IMP]
- regulation of apoptotic cell clearance [IDA]
- regulation of bone resorption [TAS]
- regulation of ion transmembrane transport [ISO]
- regulation of phagocytosis [ISO, NAS]
- release of sequestered calcium ion into cytosol [TAS]
- response to nitric oxide [TAS]
- substrate adhesion-dependent cell spreading [ISO]
- trophoblast giant cell differentiation [TAS]
- viral entry into host cell [ISO]
Gene Ontology Molecular Function- extracellular matrix binding [ISO]
- extracellular matrix protein binding [ISO]
- fibronectin binding [ISO]
- insulin-like growth factor I binding [ISO]
- opsonin binding [IDA]
- peptide binding [ISO]
- protease binding [ISO]
- protein heterodimerization activity [TAS]
- protein kinase C binding [IDA]
- receptor binding [ISO]
- voltage-gated calcium channel activity [ISO]
- extracellular matrix binding [ISO]
- extracellular matrix protein binding [ISO]
- fibronectin binding [ISO]
- insulin-like growth factor I binding [ISO]
- opsonin binding [IDA]
- peptide binding [ISO]
- protease binding [ISO]
- protein heterodimerization activity [TAS]
- protein kinase C binding [IDA]
- receptor binding [ISO]
- voltage-gated calcium channel activity [ISO]
Gene Ontology Cellular Component
- alphav-beta3 integrin-IGF-1-IGF1R complex [ISO]
- cell surface [ISO]
- cytosol [ISO]
- external side of plasma membrane [IDA]
- extracellular vesicular exosome [ISO]
- filopodium membrane [ISO]
- focal adhesion [ISO]
- integrin alphav-beta3 complex [ISO, TAS]
- integrin alphav-beta5 complex [ISO]
- integrin alphav-beta8 complex [ISO]
- integrin complex [ISO]
- intracellular [IDA]
- lamellipodium membrane [ISO]
- membrane [IDA]
- microvillus membrane [ISO]
- nucleus [ISO]
- plasma membrane [IDA, ISO]
- ruffle membrane [ISO]
Download Curated Data for this Protein
200824
10090
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- Interactors 4
- Interactions 5
- Network