Mus musculus
KLF4
EZF, Gklf, Zie, RP23-322L22.2
Kruppel-like factor 4 (gut)
GO Process (39)
GO Function (16)
GO Component (7)
Gene Ontology Biological Process
- canonical Wnt signaling pathway [IMP]
- cell differentiation [IMP]
- cellular response to growth factor stimulus [ISO]
- cellular response to laminar fluid shear stress [ISO]
- epidermal cell differentiation [IMP]
- epidermis morphogenesis [IMP]
- fat cell differentiation [IMP]
- negative regulation of ERK1 and ERK2 cascade [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of cell migration involved in sprouting angiogenesis [ISO]
- negative regulation of cell proliferation [IDA]
- negative regulation of chemokine (C-X-C motif) ligand 2 production [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of heterotypic cell-cell adhesion [ISO]
- negative regulation of interleukin-8 biosynthetic process [ISO]
- negative regulation of muscle hyperplasia [ISO]
- negative regulation of phosphatidylinositol 3-kinase signaling [ISO]
- negative regulation of protein kinase B signaling [ISO]
- negative regulation of response to cytokine stimulus [ISO]
- negative regulation of smooth muscle cell proliferation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO, ISS, NAS]
- positive regulation of cellular protein metabolic process [ISO]
- positive regulation of hemoglobin biosynthetic process [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- positive regulation of protein metabolic process [ISO]
- positive regulation of telomerase activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- positive regulation of transcription, DNA-templated [IDA]
- post-embryonic camera-type eye development [IMP]
- post-embryonic hemopoiesis [ISO]
- regulation of cell differentiation [IDA]
- regulation of cell proliferation [IGI]
- regulation of phosphatidylinositol 3-kinase activity [ISO]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to organic substance [IDA]
- response to retinoic acid [IDA]
- stem cell maintenance [IDA]
- transcription from RNA polymerase II promoter [IDA, ISO]
Gene Ontology Molecular Function- DNA binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II transcription factor binding [IPI, ISO]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [ISO]
- beta-catenin binding [IPI]
- core promoter binding [IDA]
- core promoter proximal region sequence-specific DNA binding [ISO]
- double-stranded DNA binding [ISO]
- histone deacetylase binding [ISO]
- phosphatidylinositol 3-kinase regulator activity [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- sequence-specific DNA binding transcription factor recruiting transcription factor activity [IDA]
- transcription cofactor binding [ISO]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, ISO]
- DNA binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II transcription factor binding [IPI, ISO]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [ISO]
- beta-catenin binding [IPI]
- core promoter binding [IDA]
- core promoter proximal region sequence-specific DNA binding [ISO]
- double-stranded DNA binding [ISO]
- histone deacetylase binding [ISO]
- phosphatidylinositol 3-kinase regulator activity [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- sequence-specific DNA binding transcription factor recruiting transcription factor activity [IDA]
- transcription cofactor binding [ISO]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
200966
10090
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- Interactors 16
- Interactions 20
- Network