Mus musculus
LEF1
3000002B05, AI451430, Lef-1
lymphoid enhancer binding factor 1
GO Process (74)
GO Function (22)
GO Component (4)
Gene Ontology Biological Process
- B cell proliferation [IMP]
- BMP signaling pathway [IDA]
- T cell receptor V(D)J recombination [IGI]
- T-helper 1 cell differentiation [IDA]
- Wnt signaling pathway [IDA, IGI, IMP, ISO]
- alpha-beta T cell differentiation [IGI]
- anatomical structure regression [IMP]
- apoptotic process involved in morphogenesis [IMP]
- apoptotic process involved in patterning of blood vessels [IMP]
- canonical Wnt signaling pathway [IBA, ISO]
- cell chemotaxis [ISO]
- cell development [IGI]
- cellular response to cytokine stimulus [ISO]
- cellular response to interleukin-4 [ISO]
- chorio-allantoic fusion [IGI]
- dentate gyrus development [IMP]
- embryonic limb morphogenesis [IGI]
- epithelial to mesenchymal transition [IMP]
- eye pigmentation [IBA]
- face morphogenesis [IGI]
- forebrain neuroblast division [IGI]
- forebrain neuron differentiation [IBA]
- forebrain radial glial cell differentiation [IGI]
- formation of radial glial scaffolds [IGI]
- hippocampus development [IMP]
- histone H3 acetylation [ISO]
- histone H4 acetylation [ISO]
- hypothalamus development [IBA]
- mammary gland development [IMP]
- muscle fiber development [IBA]
- negative regulation of DNA binding [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of apoptotic process in bone marrow [IBA, ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of cell-cell adhesion [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IBA, ISO]
- negative regulation of estrogen receptor binding [ISO]
- negative regulation of interleukin-13 production [IBA, ISO]
- negative regulation of interleukin-4 production [IBA, ISO]
- negative regulation of interleukin-5 production [IBA, ISO]
- negative regulation of striated muscle tissue development [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- neural crest cell migration [IBA]
- neutrophil differentiation [IBA, ISO]
- odontoblast differentiation [IBA, ISO]
- odontogenesis of dentin-containing tooth [IGI, IMP]
- osteoblast differentiation [IBA]
- palate development [IMP]
- paraxial mesoderm formation [IGI]
- patterning of blood vessels [IMP]
- positive regulation by host of viral transcription [ISO]
- positive regulation of cell cycle process [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cell proliferation in bone marrow [IBA, ISO]
- positive regulation of cell-cell adhesion [ISO]
- positive regulation of epithelial to mesenchymal transition [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of granulocyte differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISO]
- regulation of Wnt signaling pathway [IGI]
- regulation of cell-cell adhesion [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- sensory perception of taste [IMP]
- somitogenesis [IGI, IMP]
- sprouting angiogenesis [IMP]
- steroid hormone mediated signaling pathway [ISO]
- tongue development [IMP]
- trachea gland development [IMP]
- transcription from RNA polymerase II promoter [IGI, ISO]
- vasculature development [IMP]
Gene Ontology Molecular Function- C2H2 zinc finger domain binding [ISO]
- DNA binding [IDA]
- DNA binding, bending [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IGI]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- armadillo repeat domain binding [IBA, ISO]
- beta-catenin binding [IBA, ISO]
- chromatin binding [IDA]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISO]
- enhancer binding [IBA, ISO]
- estrogen receptor activity [ISO]
- estrogen receptor binding [IBA, ISO]
- gamma-catenin binding [IBA, ISO]
- histone binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [IBA, IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, ISO]
- C2H2 zinc finger domain binding [ISO]
- DNA binding [IDA]
- DNA binding, bending [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IGI]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- armadillo repeat domain binding [IBA, ISO]
- beta-catenin binding [IBA, ISO]
- chromatin binding [IDA]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISO]
- enhancer binding [IBA, ISO]
- estrogen receptor activity [ISO]
- estrogen receptor binding [IBA, ISO]
- gamma-catenin binding [IBA, ISO]
- histone binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [IBA, IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, ISO]
Download Curated Data for this Protein
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- Interactors 17
- Interactions 33
- Network