Mus musculus
LRP6
C030016K15Rik, Cd, Gw, ska26, ska, skax26
low density lipoprotein receptor-related protein 6
GO Process (91)
GO Function (13)
GO Component (12)
Gene Ontology Biological Process
- Wnt signaling pathway [IGI, ISO]
- Wnt signaling pathway involved in dorsal/ventral axis specification [IBA, ISO]
- Wnt signaling pathway involved in forebrain neuroblast division [IGI, IMP]
- Wnt signaling pathway involved in somitogenesis [IMP]
- anterior/posterior pattern specification [IGI, IMP]
- axis elongation [IMP]
- axis elongation involved in somitogenesis [IGI]
- bone morphogenesis [IMP]
- bone remodeling [IGI]
- branching involved in mammary gland duct morphogenesis [IMP]
- canonical Wnt signaling pathway [IGI, IMP, ISO]
- canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [IMP]
- canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [IMP]
- cell migration involved in gastrulation [IGI]
- cellular response to cholesterol [ISO]
- cerebellum morphogenesis [IMP]
- cerebral cortex cell migration [IMP]
- cerebral cortex development [IMP]
- convergent extension [IGI]
- dopaminergic neuron differentiation [IMP]
- dorsal/ventral axis specification [IMP]
- embryonic camera-type eye morphogenesis [IMP]
- embryonic digit morphogenesis [IGI, IMP]
- embryonic forelimb morphogenesis [IGI, IMP]
- embryonic hindlimb morphogenesis [IGI, IMP]
- embryonic limb morphogenesis [IGI]
- embryonic pattern specification [IMP]
- embryonic retina morphogenesis in camera-type eye [IMP]
- external genitalia morphogenesis [IMP]
- face morphogenesis [IMP]
- forebrain development [IMP]
- forebrain generation of neurons [IMP]
- forebrain radial glial cell differentiation [IGI]
- formation of radial glial scaffolds [IGI]
- gastrulation with mouth forming second [IGI]
- generation of neurons [IMP]
- heart looping [IGI]
- limb morphogenesis [IGI, IMP]
- mammary gland duct morphogenesis [IGI]
- mammary placode formation [IMP]
- midbrain development [IMP]
- midbrain-hindbrain boundary development [IMP]
- morphogenesis of an epithelium [IMP]
- negative regulation of Wnt signaling pathway [IGI]
- negative regulation of epithelial cell proliferation [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of non-canonical Wnt signaling pathway [IGI]
- negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [IGI]
- negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [IGI]
- negative regulation of planar cell polarity pathway involved in neural tube closure [IGI]
- negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [IGI]
- negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [IGI]
- negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [IGI]
- negative regulation of protein kinase activity [ISO]
- negative regulation of protein phosphorylation [ISO]
- negative regulation of protein serine/threonine kinase activity [ISO]
- negative regulation of smooth muscle cell apoptotic process [ISO]
- neural crest cell differentiation [ISO]
- neural crest formation [IBA, ISO]
- neural tube closure [IGI, IMP]
- neural tube development [IGI]
- odontogenesis of dentin-containing tooth [IMP]
- palate development [IMP]
- pericardium morphogenesis [IGI]
- positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [ISO]
- positive regulation of apoptotic process [IMP]
- positive regulation of bone resorption [IMP]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of cell cycle [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of ossification [IMP]
- positive regulation of sequence-specific DNA binding transcription factor activity [IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter [IBA, ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- post-anal tail morphogenesis [IGI, IMP]
- primitive streak formation [IGI]
- receptor-mediated endocytosis [IBA]
- receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [IMP]
- regulation of cell development [IMP]
- regulation of cell proliferation [IMP]
- regulation of transcription, DNA-templated [ISO]
- response to folic acid [IMP]
- retina morphogenesis in camera-type eye [IMP]
- single organismal cell-cell adhesion [ISO]
- skeletal system morphogenesis [IMP]
- somitogenesis [IGI]
- synaptic transmission [IBA, ISO]
- thalamus development [IMP]
- toxin transport [IMP, ISO]
- trachea cartilage morphogenesis [IGI]
Gene Ontology Molecular Function- Wnt-activated receptor activity [IBA]
- Wnt-protein binding [IPI, ISO]
- apolipoprotein binding [IPI]
- coreceptor activity [IBA]
- coreceptor activity involved in Wnt signaling pathway [ISO]
- frizzled binding [ISO]
- identical protein binding [ISO]
- kinase inhibitor activity [ISO]
- low-density lipoprotein receptor activity [IBA, ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- toxin transporter activity [IMP]
- Wnt-activated receptor activity [IBA]
- Wnt-protein binding [IPI, ISO]
- apolipoprotein binding [IPI]
- coreceptor activity [IBA]
- coreceptor activity involved in Wnt signaling pathway [ISO]
- frizzled binding [ISO]
- identical protein binding [ISO]
- kinase inhibitor activity [ISO]
- low-density lipoprotein receptor activity [IBA, ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- toxin transporter activity [IMP]
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- caveola [IBA, ISO]
- cell [IMP]
- cell surface [IBA, ISO]
- cytoplasmic vesicle [ISO]
- cytosol [ISO]
- early endosome [IDA, ISO]
- membrane [IDA]
- neuronal cell body [IBA, ISO]
- plasma membrane [IDA, IGI, ISO]
- receptor complex [IBA]
- synapse [IBA, ISO]
Download Curated Data for this Protein
201203
10090
Switch View:
- Interactors 13
- Interactions 27
- Network