The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator.
We here demonstrated that the Soh1/MED31 protein is a stable component of Mediator complex isolated from Schizosaccharomyces pombe and Saccharomyces cerevisiae. Bioinformatic analysis traces the Soh1/MED31 family of Mediator subunits to the point of major eukaryotic divergence, before the appearance of the canonical heptapeptide repeat structure of the RNA polymerase ... II C-terminal domain.
Mesh Terms:
Amino Acid Motifs, Amino Acid Sequence, Animals, Computational Biology, Conserved Sequence, Electrophoresis, Polyacrylamide Gel, Escherichia coli, Evolution, Molecular, Glutathione Transferase, Humans, Immunoblotting, Macromolecular Substances, Mediator Complex, Molecular Sequence Data, Plasmids, Protein Structure, Tertiary, Protein Subunits, RNA Polymerase II, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Sequence Homology, Amino Acid
Amino Acid Motifs, Amino Acid Sequence, Animals, Computational Biology, Conserved Sequence, Electrophoresis, Polyacrylamide Gel, Escherichia coli, Evolution, Molecular, Glutathione Transferase, Humans, Immunoblotting, Macromolecular Substances, Mediator Complex, Molecular Sequence Data, Plasmids, Protein Structure, Tertiary, Protein Subunits, RNA Polymerase II, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Sequence Homology, Amino Acid
J. Biol. Chem.
Date: Nov. 19, 2004
PubMed ID: 15356001
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