Mus musculus
NOTCH1
9930111A19Rik, Mis6, N1, Tan1, lin-12, RP23-306D20.12-001
notch 1
GO Process (135)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- Notch signaling involved in heart development [IGI, IMP, ISO]
- Notch signaling pathway [IC, IDA, IMP, ISO]
- Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [IMP]
- anagen [IMP]
- aortic valve morphogenesis [ISO]
- apoptotic process involved in embryonic digit morphogenesis [IMP]
- arterial endothelial cell differentiation [IMP]
- astrocyte differentiation [ISO]
- atrioventricular node development [IMP]
- atrioventricular valve morphogenesis [IMP]
- auditory receptor cell fate commitment [IMP]
- axonogenesis [IDA, IMP]
- branching morphogenesis of an epithelial tube [IMP]
- cardiac atrium morphogenesis [IMP]
- cardiac chamber formation [IMP]
- cardiac epithelial to mesenchymal transition [IMP]
- cardiac left ventricle morphogenesis [IMP]
- cardiac muscle cell proliferation [IMP]
- cardiac muscle tissue morphogenesis [IMP]
- cardiac right atrium morphogenesis [IMP]
- cardiac right ventricle formation [IMP]
- cardiac septum morphogenesis [IMP]
- cardiac vascular smooth muscle cell development [IMP]
- cardiac ventricle morphogenesis [IMP]
- cell differentiation [IMP]
- cell fate commitment [IMP]
- cell fate specification [IMP]
- cell migration involved in endocardial cushion formation [IMP]
- cellular response to follicle-stimulating hormone stimulus [ISO]
- cellular response to vascular endothelial growth factor stimulus [ISO]
- compartment pattern specification [IMP]
- coronary artery morphogenesis [IMP]
- coronary vein morphogenesis [IMP]
- determination of left/right symmetry [IMP]
- embryonic hindlimb morphogenesis [IMP]
- embryonic limb morphogenesis [IGI]
- endocardial cell differentiation [IMP]
- endocardial cushion morphogenesis [IMP]
- endocardium development [IMP]
- endocardium morphogenesis [IMP]
- endoderm development [IMP]
- epidermis development [IGI]
- epithelial to mesenchymal transition [IMP]
- epithelial to mesenchymal transition involved in endocardial cushion formation [IMP]
- forebrain development [IGI, IMP]
- foregut morphogenesis [IMP]
- glial cell differentiation [IMP]
- growth involved in heart morphogenesis [IMP]
- hair follicle morphogenesis [IMP]
- heart development [IMP, ISO]
- heart looping [IGI]
- heart trabecula morphogenesis [IMP]
- humoral immune response [IGI]
- in utero embryonic development [IMP]
- inflammatory response to antigenic stimulus [IGI]
- interleukin-4 secretion [IGI]
- keratinocyte differentiation [IMP]
- left/right axis specification [IGI]
- liver development [IMP]
- lung development [IMP]
- mesenchymal cell development [IMP]
- mitral valve formation [ISO]
- negative regulation of BMP signaling pathway [IMP]
- negative regulation of anoikis [ISO]
- negative regulation of calcium ion-dependent exocytosis [IMP]
- negative regulation of canonical Wnt signaling pathway [IMP]
- negative regulation of catalytic activity [IDA]
- negative regulation of cell death [IMP]
- negative regulation of cell differentiation [IMP]
- negative regulation of cell migration involved in sprouting angiogenesis [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of cell-substrate adhesion [ISO]
- negative regulation of endothelial cell chemotaxis [ISO]
- negative regulation of glial cell proliferation [IDA]
- negative regulation of myoblast differentiation [ISO]
- negative regulation of myotube differentiation [IDA]
- negative regulation of neurogenesis [IDA]
- negative regulation of neuron differentiation [IGI, IMP, ISO]
- negative regulation of oligodendrocyte differentiation [IDA]
- negative regulation of ossification [IMP]
- negative regulation of osteoblast differentiation [IMP]
- negative regulation of photoreceptor cell differentiation [IMP]
- negative regulation of pro-B cell differentiation [IMP]
- negative regulation of stem cell differentiation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- neural tube development [IMP]
- neuron differentiation [IMP]
- neuron fate commitment [IGI]
- osteoblast fate commitment [NAS]
- pericardium morphogenesis [IMP]
- positive regulation of BMP signaling pathway [IDA]
- positive regulation of JAK-STAT cascade [IDA]
- positive regulation of apoptotic process [IDA, IGI]
- positive regulation of astrocyte differentiation [IDA]
- positive regulation of cardiac muscle cell proliferation [IMP]
- positive regulation of cell migration [IMP]
- positive regulation of cell proliferation [IGI, ISO]
- positive regulation of endothelial cell differentiation [ISO]
- positive regulation of ephrin receptor signaling pathway [IC]
- positive regulation of epithelial cell proliferation [IGI]
- positive regulation of epithelial to mesenchymal transition [IMP, ISO]
- positive regulation of glial cell differentiation [ISO]
- positive regulation of keratinocyte differentiation [IDA, IGI]
- positive regulation of neuroblast proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [IDA]
- positive regulation of transcription of Notch receptor target [IGI, ISO]
- positive regulation of transcription, DNA-templated [IDA]
- prostate gland epithelium morphogenesis [IMP]
- pulmonary valve morphogenesis [ISO]
- regulation of cardioblast proliferation [ISO]
- regulation of cell adhesion involved in heart morphogenesis [IC]
- regulation of cell migration [IMP]
- regulation of cell proliferation [ISO]
- regulation of epithelial cell proliferation [IMP]
- regulation of epithelial cell proliferation involved in prostate gland development [IMP]
- regulation of extracellular matrix assembly [IMP]
- regulation of gene expression [IMP]
- regulation of neurogenesis [IMP]
- regulation of somitogenesis [IMP]
- regulation of transcription from RNA polymerase II promoter [IGI]
- regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [IMP]
- response to muramyl dipeptide [IDA]
- secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [IMP]
- skeletal muscle cell differentiation [IMP]
- somatic stem cell division [IDA, IGI]
- spermatogenesis [ISO]
- sprouting angiogenesis [IMP]
- transcription from RNA polymerase II promoter [IDA]
- tube formation [ISO]
- vasculogenesis involved in coronary vascular morphogenesis [IMP]
- venous endothelial cell differentiation [IMP]
- ventricular septum morphogenesis [ISO]
- ventricular trabecula myocardium morphogenesis [IMP]
Gene Ontology Molecular Function- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- core promoter binding [IDA]
- enzyme binding [IPI]
- enzyme inhibitor activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- core promoter binding [IDA]
- enzyme binding [IPI]
- enzyme inhibitor activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
201808
10090
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- Interactors 32
- Interactions 43
- Network
- PTM Sites 1