Mus musculus
PDGFB
PDGF-B, Sis
platelet derived growth factor, B polypeptide
GO Process (64)
GO Function (10)
GO Component (4)
Gene Ontology Biological Process
- actin cytoskeleton organization [IDA, IGI]
- activation of protein kinase B activity [ISO]
- activation of protein kinase activity [ISO]
- blood coagulation [IBA]
- blood vessel morphogenesis [IDA, IGI]
- branching involved in salivary gland morphogenesis [IMP]
- cardiac vascular smooth muscle cell differentiation [TAS]
- cell chemotaxis [ISO]
- cell projection assembly [IDA]
- cellular response to growth factor stimulus [ISO]
- cellular response to mycophenolic acid [ISO]
- embryonic placenta development [IMP]
- epithelial cell proliferation involved in salivary gland morphogenesis [IMP]
- heart development [IMP]
- metanephric glomerular mesangial cell development [IMP]
- metanephric glomerular mesangial cell proliferation involved in metanephros development [IMP]
- monocyte chemotaxis [ISO]
- negative regulation of cell migration [IGI]
- negative regulation of phosphatidylinositol biosynthetic process [ISO]
- negative regulation of platelet activation [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of vasodilation [TAS]
- paracrine signaling [IMP]
- peptidyl-serine phosphorylation [ISO]
- peptidyl-tyrosine phosphorylation [ISO]
- platelet-derived growth factor receptor signaling pathway [IBA, ISO]
- positive chemotaxis [ISO]
- positive regulation of DNA biosynthetic process [ISO]
- positive regulation of DNA replication [ISO]
- positive regulation of ERK1 and ERK2 cascade [IBA, ISO]
- positive regulation of MAP kinase activity [IBA, ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of calcium ion import [ISO]
- positive regulation of cell migration [IGI, ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity [ISO]
- positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [TAS]
- positive regulation of endothelial cell proliferation [IGI, ISO]
- positive regulation of fibroblast growth factor receptor signaling pathway [IDA]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of glomerular filtration [IMP]
- positive regulation of glomerular mesangial cell proliferation [ISO]
- positive regulation of hyaluronan biosynthetic process [ISO]
- positive regulation of metanephric mesenchymal cell migration [ISO]
- positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [ISO]
- positive regulation of mitosis [ISO]
- positive regulation of mitotic cell cycle, embryonic [IGI]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [IGI, ISO]
- positive regulation of protein autophosphorylation [IBA, ISO]
- positive regulation of protein tyrosine kinase activity [ISO]
- positive regulation of reactive oxygen species metabolic process [ISO]
- positive regulation of smooth muscle cell migration [IMP, ISO]
- positive regulation of smooth muscle cell proliferation [IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- positive regulation of vasoconstriction [TAS]
- protein phosphorylation [ISO]
- reactive oxygen species metabolic process [ISO]
- regulation of peptidyl-tyrosine phosphorylation [IDA]
- response to wounding [ISO]
- substrate-dependent cell migration [IDA]
Gene Ontology Molecular Function- chemoattractant activity [ISO]
- collagen binding [ISO]
- growth factor activity [ISO]
- identical protein binding [ISO]
- platelet-derived growth factor binding [ISO]
- platelet-derived growth factor receptor binding [IBA, ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- superoxide-generating NADPH oxidase activator activity [ISO]
- chemoattractant activity [ISO]
- collagen binding [ISO]
- growth factor activity [ISO]
- identical protein binding [ISO]
- platelet-derived growth factor binding [ISO]
- platelet-derived growth factor receptor binding [IBA, ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- superoxide-generating NADPH oxidase activator activity [ISO]
Gene Ontology Cellular Component
202087
10090