Mus musculus
PDGFRB
AI528809, CD140b, PDGFR-1, Pdgfr
platelet derived growth factor receptor, beta polypeptide
GO Process (52)
GO Function (12)
GO Component (9)
Gene Ontology Biological Process
- adrenal gland development [IGI]
- aorta morphogenesis [IGI]
- cardiac myofibril assembly [IGI]
- cardiac vascular smooth muscle cell differentiation [TAS]
- cell chemotaxis [ISO]
- cell migration [ISO]
- cell migration involved in coronary angiogenesis [IMP]
- cell migration involved in vasculogenesis [IMP]
- cellular response to platelet-derived growth factor stimulus [ISO]
- glycosaminoglycan biosynthetic process [ISO]
- hemopoiesis [IMP]
- in utero embryonic development [IMP]
- intracellular signal transduction [ISO]
- kidney development [IMP]
- metanephric glomerular capillary formation [IGI]
- metanephric glomerular mesangial cell proliferation involved in metanephros development [IMP]
- metanephric mesenchymal cell migration [ISO]
- negative regulation of apoptotic process [ISO]
- nitrogen compound metabolic process [IMP]
- peptidyl-tyrosine phosphorylation [IDA, ISO]
- phosphatidylinositol metabolic process [ISO]
- phosphatidylinositol-mediated signaling [ISO]
- phosphorylation [IMP]
- platelet-derived growth factor receptor signaling pathway [IMP, ISO]
- platelet-derived growth factor receptor-beta signaling pathway [ISO]
- positive regulation of DNA biosynthetic process [IMP]
- positive regulation of ERK1 and ERK2 cascade [IDA, IMP, ISO]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of calcium ion import [IMP]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [ISO]
- positive regulation of chemotaxis [IDA]
- positive regulation of collagen biosynthetic process [ISO]
- positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [IMP]
- positive regulation of mitosis [IDA]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [IDA]
- positive regulation of phospholipase C activity [ISO]
- positive regulation of phosphoprotein phosphatase activity [ISO]
- positive regulation of reactive oxygen species metabolic process [IMP]
- positive regulation of smooth muscle cell migration [IGI, IMP, ISO]
- positive regulation of smooth muscle cell proliferation [IMP, ISO]
- protein autophosphorylation [IDA, ISO]
- regulation of actin cytoskeleton organization [IGI]
- regulation of peptidyl-tyrosine phosphorylation [IMP]
- retina vasculature development in camera-type eye [IGI, IMP]
- signal transduction [IDA, ISO]
- skeletal system morphogenesis [IMP]
- smooth muscle cell chemotaxis [IGI]
- smooth muscle tissue development [IMP]
- tissue homeostasis [IMP]
Gene Ontology Molecular Function- kinase activity [IMP]
- phosphatidylinositol 3-kinase binding [ISO]
- platelet-derived growth factor beta-receptor activity [ISO]
- platelet-derived growth factor binding [ISO, TAS]
- platelet-derived growth factor receptor binding [ISO]
- platelet-derived growth factor-activated receptor activity [ISO]
- protein binding [IPI]
- protein kinase binding [ISO]
- protein tyrosine kinase activity [ISO]
- receptor binding [IPI, ISO]
- signal transducer activity [IDA]
- vascular endothelial growth factor binding [ISO]
- kinase activity [IMP]
- phosphatidylinositol 3-kinase binding [ISO]
- platelet-derived growth factor beta-receptor activity [ISO]
- platelet-derived growth factor binding [ISO, TAS]
- platelet-derived growth factor receptor binding [ISO]
- platelet-derived growth factor-activated receptor activity [ISO]
- protein binding [IPI]
- protein kinase binding [ISO]
- protein tyrosine kinase activity [ISO]
- receptor binding [IPI, ISO]
- signal transducer activity [IDA]
- vascular endothelial growth factor binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 14
- Interactions 20
- Network
- PTM Sites 1