Mus musculus
PDX1
IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
pancreatic and duodenal homeobox 1
GO Process (32)
GO Function (11)
GO Component (4)
Gene Ontology Biological Process
- cell differentiation [IMP, ISO]
- detection of glucose [ISO]
- digestive tract development [IMP]
- endocrine pancreas development [IMP]
- exocrine pancreas development [IMP]
- glucose homeostasis [IGI, IMP, ISO]
- glucose metabolic process [IDA]
- insulin secretion [ISO]
- liver development [IMP]
- morphogenesis of embryonic epithelium [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of type B pancreatic cell apoptotic process [IMP]
- nitric oxide mediated signal transduction [ISO]
- pancreas development [IMP]
- positive regulation of DNA binding [ISO]
- positive regulation of cell death [ISO]
- positive regulation of cell proliferation [IMP, ISO]
- positive regulation of insulin secretion [ISO]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- regulation of cell proliferation [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- response to glucose [ISO]
- smoothened signaling pathway [ISO]
- stem cell differentiation [ISO]
- transcription from RNA polymerase II promoter [ISO]
- transcription, DNA-templated [ISO]
- type B pancreatic cell differentiation [ISO]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- chromatin binding [IDA]
- core promoter sequence-specific DNA binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- chromatin binding [IDA]
- core promoter sequence-specific DNA binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
202101
10090
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- Interactors 6
- Interactions 16
- Network