Mus musculus
PITX2
9430085M16Rik, Brx1, Brx1b, Munc30, Otlx2, Ptx2, Rieg
paired-like homeodomain transcription factor 2
GO Process (50)
GO Function (19)
GO Component (4)
Gene Ontology Biological Process
- Wnt signaling pathway [IDA]
- anatomical structure morphogenesis [IMP]
- atrial cardiac muscle tissue morphogenesis [IMP]
- atrioventricular valve development [IMP]
- camera-type eye development [ISO]
- cardiac muscle cell differentiation [IMP]
- cardiac muscle tissue development [IMP]
- cardiac neural crest cell migration involved in outflow tract morphogenesis [IMP]
- cell proliferation involved in outflow tract morphogenesis [IMP]
- deltoid tuberosity development [IMP, ISO]
- determination of left/right symmetry [IMP]
- digestive system development [IMP]
- embryonic camera-type eye development [IMP]
- embryonic digestive tract morphogenesis [IMP]
- embryonic hindlimb morphogenesis [IGI]
- endodermal digestive tract morphogenesis [IMP]
- extraocular skeletal muscle development [IMP]
- heart development [IGI, IMP]
- hypothalamus cell migration [IMP]
- in utero embryonic development [IMP]
- iris morphogenesis [ISO]
- left lung morphogenesis [IMP]
- left/right axis specification [IMP]
- lung development [IMP]
- myoblast fusion [IDA]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- neuron migration [IMP]
- odontogenesis [IMP, ISO]
- organ morphogenesis [IMP]
- patterning of blood vessels [IMP]
- pituitary gland development [IMP]
- positive regulation of DNA binding [IDA]
- positive regulation of myoblast proliferation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [IMP]
- pulmonary myocardium development [IMP]
- pulmonary vein morphogenesis [IMP]
- regulation of cell migration [IMP]
- regulation of cell proliferation [IMP]
- regulation of transcription from RNA polymerase II promoter [IGI, ISO]
- regulation of transcription, DNA-templated [IDA, ISO]
- skeletal muscle tissue development [IMP]
- spleen development [IMP]
- subthalamic nucleus development [IMP]
- superior vena cava morphogenesis [IMP]
- transcription from RNA polymerase II promoter [ISO]
- vascular smooth muscle cell differentiation [IMP]
- vasculogenesis [IMP]
- ventricular cardiac muscle cell development [IMP]
- ventricular septum morphogenesis [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II transcription coactivator activity [ISO]
- RNA polymerase II transcription factor binding [ISO]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [ISO]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- identical protein binding [ISO]
- phosphoprotein binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region sequence-specific DNA binding [ISO]
- DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II transcription coactivator activity [ISO]
- RNA polymerase II transcription factor binding [ISO]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [ISO]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- identical protein binding [ISO]
- phosphoprotein binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region sequence-specific DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
202187
10090
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- Interactors 3
- Interactions 4
- Network