Mus musculus
PML
1200009E24Rik, AI661194, Trim19
promyelocytic leukemia
GO Process (56)
GO Function (9)
GO Component (10)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [IMP]
- PML body organization [IDA, ISO]
- SMAD protein import into nucleus [IMP]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- apoptotic process [ISO]
- branching involved in mammary gland duct morphogenesis [IMP]
- cell aging [IMP]
- cell cycle arrest [IMP, ISO]
- cell fate commitment [IMP]
- cellular response to interleukin-4 [IDA]
- cellular senescence [ISO]
- circadian regulation of gene expression [IDA]
- common-partner SMAD protein phosphorylation [IMP]
- endoplasmic reticulum calcium ion homeostasis [IMP]
- entrainment of circadian clock by photoperiod [IDA]
- extrinsic apoptotic signaling pathway [IMP]
- innate immune response [IDA, ISO]
- intrinsic apoptotic signaling pathway by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP, ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IMP]
- intrinsic apoptotic signaling pathway in response to oxidative stress [IMP]
- maintenance of protein location in nucleus [ISO]
- myeloid cell differentiation [IMP]
- negative regulation of angiogenesis [IMP, ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP, ISO]
- negative regulation of mitotic cell cycle [ISO]
- negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- negative regulation of telomerase activity [ISO]
- negative regulation of telomere maintenance via telomerase [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of translation in response to oxidative stress [ISO]
- negative regulation of viral release from host cell [IDA, ISO]
- positive regulation of apoptotic process involved in mammary gland involution [ISO]
- positive regulation of apoptotic signaling pathway [IGI, IMP]
- positive regulation of defense response to virus by host [ISO]
- positive regulation of extrinsic apoptotic signaling pathway [ISO]
- positive regulation of histone deacetylation [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- protein complex assembly [ISO]
- protein stabilization [ISO]
- protein targeting [ISO]
- regulation of MHC class I biosynthetic process [IDA]
- regulation of calcium ion transport into cytosol [IMP]
- regulation of circadian rhythm [IDA]
- regulation of double-strand break repair [ISO]
- regulation of nucleic acid-templated transcription [TAS]
- regulation of protein phosphorylation [IMP]
- regulation of transcription, DNA-templated [IDA, ISO]
- response to UV [IMP]
- response to cytokine [ISO]
- response to gamma radiation [IMP]
- response to hypoxia [IMP, ISO]
- retinoic acid receptor signaling pathway [IMP]
- transforming growth factor beta receptor signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
202265
10090
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- Interactors 28
- Interactions 35
- Network
- PTM Sites 6