Mus musculus
EIF2AK2
2310047A08Rik, 4732414G15Rik, AI467567, AI747578, Pkr, Prkr, Tik
eukaryotic translation initiation factor 2-alpha kinase 2
GO Process (24)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- activation of MAPKK activity [ISO]
- endoplasmic reticulum unfolded protein response [IDA]
- negative regulation of apoptotic process [IGI]
- negative regulation of osteoblast proliferation [ISO]
- negative regulation of translation [ISO]
- negative regulation of viral genome replication [IMP, ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of NIK/NF-kappaB signaling [IMP]
- positive regulation of apoptotic process [ISO]
- positive regulation of chemokine production [IMP]
- positive regulation of cytokine production [IMP]
- positive regulation of stress-activated MAPK cascade [IMP]
- protein autophosphorylation [IDA, ISO]
- protein phosphorylation [IDA, IMP, ISO]
- regulation of NLRP3 inflammasome complex assembly [IMP]
- regulation of hematopoietic progenitor cell differentiation [IMP]
- regulation of hematopoietic stem cell differentiation [IMP]
- regulation of hematopoietic stem cell proliferation [IMP]
- response to interferon-alpha [ISO]
- response to lipopolysaccharide [ISO]
- response to toxic substance [ISO]
- response to virus [ISO]
- response to vitamin E [ISO]
- translation [IDA]
Gene Ontology Molecular Function
Download Curated Data for this Protein
202376
10090
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- Interactors 12
- Interactions 13
- Network
- PTM Sites 4