Mus musculus
PTEN
2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, MMAC1, TEP1
phosphatase and tensin homolog
GO Process (72)
GO Function (13)
GO Component (13)
Gene Ontology Biological Process
- activation of mitotic anaphase-promoting complex activity [IMP, ISO]
- angiogenesis [IMP]
- brain morphogenesis [IMP]
- canonical Wnt signaling pathway [ISO]
- cardiac muscle tissue development [IMP]
- cell migration [IMP]
- central nervous system development [IMP]
- central nervous system myelin maintenance [IMP]
- central nervous system neuron axonogenesis [IMP]
- dendritic spine morphogenesis [IMP]
- dentate gyrus development [IMP]
- dephosphorylation [IDA]
- endothelial cell migration [IMP]
- forebrain morphogenesis [IMP]
- heart development [IMP]
- inositol phosphate dephosphorylation [ISO]
- learning or memory [IMP]
- locomotor rhythm [IMP]
- locomotory behavior [IMP]
- long term synaptic depression [ISO]
- long-term synaptic potentiation [IMP]
- male mating behavior [IMP]
- maternal behavior [IMP]
- memory [ISO]
- multicellular organismal response to stress [IMP]
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of apoptotic process [IMP]
- negative regulation of axonogenesis [IMP]
- negative regulation of cell aging [IMP]
- negative regulation of cell migration [ISO]
- negative regulation of cell proliferation [IGI, IMP, ISO]
- negative regulation of cell size [IMP]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [ISO]
- negative regulation of dendritic spine morphogenesis [IMP]
- negative regulation of epithelial cell proliferation [IMP]
- negative regulation of excitatory postsynaptic membrane potential [IMP]
- negative regulation of focal adhesion assembly [ISO]
- negative regulation of myelination [IMP]
- negative regulation of organ growth [IMP]
- negative regulation of phagocytosis [ISO]
- negative regulation of protein kinase B signaling [IMP, ISO]
- negative regulation of protein phosphorylation [ISO]
- negative regulation of ribosome biogenesis [IMP]
- negative regulation of synaptic vesicle clustering [IMP]
- neuron projection development [ISO]
- neuron-neuron synaptic transmission [IMP]
- peptidyl-tyrosine dephosphorylation [ISO]
- phosphatidylinositol dephosphorylation [ISO]
- platelet-derived growth factor receptor signaling pathway [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of apoptotic signaling pathway [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of excitatory postsynaptic membrane potential [IMP]
- positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- postsynaptic density assembly [IMP]
- prepulse inhibition [IMP]
- presynaptic membrane assembly [IMP]
- prostate gland growth [IMP]
- protein dephosphorylation [ISO]
- protein kinase B signaling [IMP]
- protein stabilization [ISO]
- regulation of B cell apoptotic process [IMP]
- regulation of cell cycle [IGI]
- regulation of cellular component size [IMP]
- regulation of myeloid cell apoptotic process [IMP]
- regulation of neuron projection development [IMP]
- regulation of protein stability [ISO]
- rhythmic synaptic transmission [IMP]
- social behavior [IMP]
- synapse assembly [IMP]
- synapse maturation [IMP]
Gene Ontology Molecular Function- PDZ domain binding [ISO]
- anaphase-promoting complex binding [ISO]
- enzyme binding [ISO]
- inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [IDA, ISO]
- phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3-phosphatase activity [ISO]
- phosphoprotein phosphatase activity [ISO]
- platelet-derived growth factor receptor binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein serine/threonine phosphatase activity [ISO]
- protein tyrosine phosphatase activity [ISO]
- PDZ domain binding [ISO]
- anaphase-promoting complex binding [ISO]
- enzyme binding [ISO]
- inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [IDA, ISO]
- phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [ISO]
- phosphatidylinositol-3-phosphatase activity [ISO]
- phosphoprotein phosphatase activity [ISO]
- platelet-derived growth factor receptor binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein serine/threonine phosphatase activity [ISO]
- protein tyrosine phosphatase activity [ISO]
Gene Ontology Cellular Component
- Schmidt-Lanterman incisure [IDA]
- cell projection [ISO]
- cytoplasm [IDA, ISO]
- cytoplasmic side of plasma membrane [ISO]
- dendritic spine [ISO]
- intracellular [IMP]
- mitochondrion [ISO]
- myelin sheath adaxonal region [IDA]
- neuron projection [IDA, ISO]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- plasma membrane [ISO]
- postsynaptic membrane [ISO]
Download Curated Data for this Protein
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10090
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- Interactors 291
- Interactions 308
- Network
- PTM Sites 2