Mus musculus
SREBF1
ADD-1, ADD1, D630008H06, SREBP-1, SREBP-1a, SREBP-1c, SREBP1, SREBP1c, bHLHd1, RP23-456O18.1
sterol regulatory element binding transcription factor 1
GO Process (17)
GO Function (11)
GO Component (6)
Gene Ontology Biological Process
- cellular response to starvation [IDA, ISO]
- cholesterol metabolic process [ISO]
- insulin receptor signaling pathway [IDA]
- lipid biosynthetic process [IDA]
- negative regulation of insulin secretion [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- positive regulation of cholesterol biosynthetic process [IMP]
- positive regulation of fatty acid biosynthetic process [TAS]
- positive regulation of histone deacetylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- positive regulation of triglyceride biosynthetic process [IDA, IMP]
- regulation of fatty acid metabolic process [IMP]
- regulation of heart rate by chemical signal [IMP]
- regulation of insulin secretion [IMP]
- regulation of transcription, DNA-templated [IDA, ISS]
- response to glucose [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [IDA, ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein kinase binding [IPI]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- sterol response element binding [ISO, ISS]
- transcription regulatory region DNA binding [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [IDA, ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein kinase binding [IPI]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- sterol response element binding [ISO, ISS]
- transcription regulatory region DNA binding [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
203495
10090
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- Interactors 12
- Interactions 16
- Network
- PTM Sites 14