Mus musculus
STAT1
2010005J02Rik, AA408197
signal transducer and activator of transcription 1
GO Process (33)
GO Function (14)
GO Component (7)
Gene Ontology Biological Process
- JAK-STAT cascade [ISO]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- blood circulation [ISO]
- cellular response to insulin stimulus [ISO]
- cellular response to interferon-beta [ISO]
- cellular response to lipopolysaccharide [IMP]
- cytokine-mediated signaling pathway [IDA]
- interferon-gamma-mediated signaling pathway [IMP, ISO]
- lipopolysaccharide-mediated signaling pathway [IDA]
- negative regulation by virus of viral protein levels in host cell [ISO]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of angiogenesis [ISO]
- negative regulation of endothelial cell proliferation [ISO]
- negative regulation of macrophage fusion [IMP]
- positive regulation of cell proliferation [ISO]
- positive regulation of smooth muscle cell proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription, DNA-templated [IMP]
- renal tubule development [ISO]
- response to bacterium [IDA]
- response to cAMP [ISO]
- response to cytokine [ISO]
- response to drug [ISO]
- response to exogenous dsRNA [IDA]
- response to lipopolysaccharide [IDA]
- response to mechanical stimulus [ISO]
- response to nutrient [ISO]
- response to peptide hormone [ISO]
- transcription from RNA polymerase II promoter [ISO]
- transcription, DNA-templated [IMP]
- tumor necrosis factor-mediated signaling pathway [ISO]
- type I interferon signaling pathway [IMP]
Gene Ontology Molecular Function- CCR5 chemokine receptor binding [ISO]
- DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISO]
- double-stranded DNA binding [ISO]
- enzyme binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein phosphatase 2A binding [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IMP]
- tumor necrosis factor receptor binding [ISO]
- CCR5 chemokine receptor binding [ISO]
- DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISO]
- double-stranded DNA binding [ISO]
- enzyme binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein phosphatase 2A binding [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IMP]
- tumor necrosis factor receptor binding [ISO]
Download Curated Data for this Protein
203521
10090
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- Interactors 33
- Interactions 37
- Network
- PTM Sites 15