Mus musculus
SYK
Sykb
spleen tyrosine kinase
GO Process (52)
GO Function (11)
GO Component (9)
Gene Ontology Biological Process
- B cell receptor signaling pathway [IDA]
- G-protein coupled receptor signaling pathway [TAS]
- activation of JUN kinase activity [IMP]
- activation of MAPK activity [IDA, IMP]
- adaptive immune response [IBA]
- beta selection [IGI]
- blood vessel morphogenesis [IMP]
- cell migration [IBA]
- cell surface receptor signaling pathway [IDA, IMP]
- cellular response to molecule of fungal origin [IMP]
- defense response to bacterium [IMP]
- enzyme linked receptor protein signaling pathway [IDA]
- innate immune response [IMP]
- integrin-mediated signaling pathway [IMP]
- intracellular signal transduction [IDA, IMP]
- leukocyte activation involved in immune response [IMP]
- leukocyte cell-cell adhesion [ISO]
- leukotriene biosynthetic process [IMP]
- lymph vessel development [IMP]
- macrophage activation involved in immune response [IMP]
- neutrophil activation involved in immune response [IMP]
- neutrophil chemotaxis [ISO]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [IDA, IMP, ISO]
- positive regulation of B cell differentiation [IMP]
- positive regulation of alpha-beta T cell differentiation [IGI]
- positive regulation of alpha-beta T cell proliferation [IGI]
- positive regulation of bone resorption [IMP]
- positive regulation of calcium-mediated signaling [IMP]
- positive regulation of cell adhesion mediated by integrin [IMP]
- positive regulation of cytokine secretion [IGI]
- positive regulation of gamma-delta T cell differentiation [IMP]
- positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [IMP]
- positive regulation of interleukin-3 biosynthetic process [IMP]
- positive regulation of mast cell degranulation [IMP, ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [IMP]
- protein autophosphorylation [IDA, ISO]
- regulation of ERK1 and ERK2 cascade [IMP]
- regulation of arachidonic acid secretion [IMP]
- regulation of immune response [ISO]
- regulation of neutrophil degranulation [IMP]
- regulation of phagocytosis [IMP]
- regulation of platelet activation [IMP]
- regulation of platelet aggregation [IMP]
- regulation of sequence-specific DNA binding transcription factor activity [ISO]
- regulation of superoxide anion generation [IMP]
- serotonin secretion [IMP]
- serotonin secretion by platelet [IMP]
- signal transduction by phosphorylation [IDA]
- transcription factor import into nucleus [ISO]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function- ATP binding [IDA]
- integrin binding [ISO]
- non-membrane spanning protein tyrosine kinase activity [IDA, ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein kinase activity [ISO]
- protein kinase binding [IPI]
- protein serine/threonine kinase activity [ISO]
- protein tyrosine kinase activity [IDA, IMP, ISO]
- receptor binding [IBA]
- receptor signaling protein tyrosine kinase activity [IDA]
- ATP binding [IDA]
- integrin binding [ISO]
- non-membrane spanning protein tyrosine kinase activity [IDA, ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein kinase activity [ISO]
- protein kinase binding [IPI]
- protein serine/threonine kinase activity [ISO]
- protein tyrosine kinase activity [IDA, IMP, ISO]
- receptor binding [IBA]
- receptor signaling protein tyrosine kinase activity [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
203599
10090
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- Interactors 18
- Interactions 21
- Network
- PTM Sites 1