Mus musculus
TCF7L2
TCF4B, TCF4E, Tcf-4, Tcf4, mTcf-4B, mTcf-4E
transcription factor 7 like 2, T cell specific, HMG box
GO Process (63)
GO Function (15)
GO Component (10)
Gene Ontology Biological Process
- Wnt signaling pathway [IDA, IGI]
- blood vessel development [ISO]
- bone mineralization [IGI]
- canonical Wnt signaling pathway [IMP]
- canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition [ISO]
- catenin import into nucleus [IDA]
- cell cycle arrest [ISO]
- cell proliferation [ISO]
- cellular glucose homeostasis [IMP]
- cellular response to starvation [IMP]
- embryonic digestive tract morphogenesis [IGI]
- embryonic genitalia morphogenesis [IGI]
- embryonic hindgut morphogenesis [IGI]
- face morphogenesis [IGI]
- fat cell differentiation [ISO]
- glucose homeostasis [IMP, ISO]
- glucose metabolic process [IMP]
- glycogen metabolic process [IMP]
- insulin metabolic process [IMP]
- maintenance of DNA repeat elements [ISO]
- multicellular organism growth [IMP]
- myoblast fate commitment [IMP, ISO]
- negative regulation of BMP signaling pathway [IMP]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of fibroblast growth factor receptor signaling pathway [IMP]
- negative regulation of organ growth [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of type B pancreatic cell apoptotic process [ISO]
- neural tube development [IGI]
- odontogenesis of dentin-containing tooth [IGI]
- oligodendrocyte development [IMP]
- pituitary gland development [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of gluconeogenesis [IMP]
- positive regulation of heparan sulfate proteoglycan biosynthetic process [ISO]
- positive regulation of insulin secretion [IMP, ISO]
- positive regulation of lipid biosynthetic process [IMP]
- positive regulation of protein binding [ISO]
- positive regulation of protein export from nucleus [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription, DNA-templated [IMP]
- positive regulation of triglyceride biosynthetic process [IMP]
- post-embryonic development [IMP]
- regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of hormone metabolic process [ISO]
- regulation of insulin secretion involved in cellular response to glucose stimulus [IMP, ISO]
- regulation of myelination [IMP]
- regulation of oligodendrocyte differentiation [IMP]
- regulation of skeletal muscle tissue development [IMP]
- regulation of smooth muscle cell proliferation [ISO]
- regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- regulation of transcription, DNA-templated [IBA, IDA]
- response to glucose [IMP]
- secretory granule localization [IMP]
- skin development [IGI]
- somatic stem cell maintenance [IGI, IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II repressing transcription factor binding [ISO]
- armadillo repeat domain binding [ISO]
- beta-catenin binding [IDA, IPI, ISO]
- chromatin binding [IDA, IGI]
- gamma-catenin binding [ISO]
- nuclear hormone receptor binding [ISO]
- protein binding [IPI]
- protein kinase binding [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IBA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II repressing transcription factor binding [ISO]
- armadillo repeat domain binding [ISO]
- beta-catenin binding [IDA, IPI, ISO]
- chromatin binding [IDA, IGI]
- gamma-catenin binding [ISO]
- nuclear hormone receptor binding [ISO]
- protein binding [IPI]
- protein kinase binding [ISO]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IBA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [IDA, ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204009
10090
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- Interactors 33
- Interactions 39
- Network