Mus musculus
TGFB1
TGF-beta1, TGFbeta1, Tgfb, Tgfb-1
transforming growth factor, beta 1
GO Process (138)
GO Function (10)
GO Component (11)
Gene Ontology Biological Process
- ATP biosynthetic process [ISO]
- MAPK cascade [ISO]
- SMAD protein complex assembly [ISO]
- SMAD protein import into nucleus [ISO]
- SMAD protein signal transduction [IBA]
- T cell activation [IDA, IMP]
- T cell differentiation [IMP]
- T cell homeostasis [IMP]
- adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [IDA]
- branch elongation involved in mammary gland duct branching [IMP]
- cell activation [IDA]
- cell cycle arrest [ISO]
- cell proliferation [IDA, TAS]
- cell-cell junction organization [ISO]
- cellular calcium ion homeostasis [IMP]
- cellular response to dexamethasone stimulus [ISO]
- cellular response to growth factor stimulus [IDA]
- cellular response to organic cyclic compound [ISO]
- cellular response to transforming growth factor beta stimulus [IDA, ISO]
- chondrocyte differentiation [ISO]
- common-partner SMAD protein phosphorylation [ISO]
- defense response [TAS]
- defense response to fungus, incompatible interaction [ISO]
- endoderm development [IDA]
- epidermal growth factor receptor signaling pathway [ISO]
- epithelial to mesenchymal transition [ISO]
- evasion or tolerance of host defenses by virus [ISO]
- extracellular matrix assembly [IDA, ISO]
- extrinsic apoptotic signaling pathway [ISO]
- germ cell migration [IDA]
- hematopoietic progenitor cell differentiation [ISO]
- hyaluronan catabolic process [ISO]
- inflammatory response [IMP, ISO]
- lens fiber cell differentiation [IMP]
- lipopolysaccharide-mediated signaling pathway [ISO]
- lymph node development [IMP]
- mammary gland branching involved in thelarche [IMP]
- mammary gland development [IDA]
- mitotic cell cycle checkpoint [ISO]
- mononuclear cell proliferation [IMP]
- morphogenesis of a branching structure [ISO]
- myelination [ISO]
- myeloid dendritic cell differentiation [IMP]
- negative regulation of DNA replication [ISO]
- negative regulation of T cell activation [IMP]
- negative regulation of T cell proliferation [IMP]
- negative regulation of blood vessel endothelial cell migration [ISO]
- negative regulation of cell cycle [ISO]
- negative regulation of cell growth [IDA, ISO]
- negative regulation of cell proliferation [ISO, TAS]
- negative regulation of cell-cell adhesion [ISO]
- negative regulation of epithelial cell proliferation [ISO]
- negative regulation of fat cell differentiation [ISO]
- negative regulation of gene expression [ISO]
- negative regulation of hyaluronan biosynthetic process [ISO]
- negative regulation of immune response [ISO]
- negative regulation of macrophage cytokine production [ISO]
- negative regulation of mitotic cell cycle [ISO]
- negative regulation of myoblast differentiation [ISO]
- negative regulation of neuroblast proliferation [ISO]
- negative regulation of ossification [IDA]
- negative regulation of phagocytosis [ISO]
- negative regulation of protein phosphorylation [ISO]
- negative regulation of release of sequestered calcium ion into cytosol [ISO]
- negative regulation of skeletal muscle tissue development [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- negative regulation of transcription, DNA-templated [ISO]
- organ morphogenesis [TAS]
- organ regeneration [ISO]
- pathway-restricted SMAD protein phosphorylation [IDA, ISO]
- phosphate-containing compound metabolic process [ISO]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of NAD+ ADP-ribosyltransferase activity [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of SMAD protein import into nucleus [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of branching involved in ureteric bud morphogenesis [ISO]
- positive regulation of cell cycle arrest [IDA]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [IDA, ISO]
- positive regulation of cellular protein metabolic process [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of collagen biosynthetic process [IDA, ISO]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of epithelial to mesenchymal transition [IDA, ISO]
- positive regulation of exit from mitosis [ISO]
- positive regulation of fibroblast migration [ISO]
- positive regulation of gene expression [IDA, ISO]
- positive regulation of histone acetylation [IDA]
- positive regulation of histone deacetylation [IDA]
- positive regulation of interleukin-17 production [IDA, ISO]
- positive regulation of isotype switching to IgA isotypes [ISO]
- positive regulation of odontogenesis [IDA]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IBA, ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of peptidyl-threonine phosphorylation [ISO]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of protein complex assembly [ISO]
- positive regulation of protein dephosphorylation [ISO]
- positive regulation of protein import into nucleus [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of protein localization to nucleus [IGI]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of protein secretion [ISO]
- positive regulation of smooth muscle cell differentiation [ISO]
- positive regulation of superoxide anion generation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription regulatory region DNA binding [ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- protein export from nucleus [ISO]
- protein import into nucleus, translocation [ISO]
- protein kinase B signaling [ISO]
- protein phosphorylation [IDA, IGI]
- receptor catabolic process [ISO]
- regulation of DNA binding [IDA]
- regulation of MAPK cascade [IBA]
- regulation of actin cytoskeleton reorganization [IGI]
- regulation of apoptotic process [IBA]
- regulation of binding [IDA]
- regulation of branching involved in mammary gland duct morphogenesis [IGI]
- regulation of cartilage development [IDA]
- regulation of cell proliferation [IDA]
- regulation of miRNA metabolic process [ISO]
- regulation of protein import into nucleus [IDA]
- regulation of sodium ion transport [IDA]
- regulation of striated muscle tissue development [IDA]
- regulation of transforming growth factor beta receptor signaling pathway [ISO]
- regulatory T cell differentiation [IDA, IMP]
- response to cholesterol [ISO]
- response to estradiol [ISO]
- response to organic substance [ISO]
- response to progesterone [ISO]
- skeletal muscle tissue development [TAS]
- skeletal system development [TAS]
- tolerance induction to self antigen [IMP]
- transforming growth factor beta receptor signaling pathway [IDA, ISO]
- wound healing [ISO]
Gene Ontology Molecular Function- antigen binding [ISO]
- cytokine activity [IBA]
- enzyme binding [ISO]
- glycoprotein binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- transforming growth factor beta receptor binding [IPI, TAS]
- type II transforming growth factor beta receptor binding [IBA, ISO]
- antigen binding [ISO]
- cytokine activity [IBA]
- enzyme binding [ISO]
- glycoprotein binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- transforming growth factor beta receptor binding [IPI, TAS]
- type II transforming growth factor beta receptor binding [IBA, ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204157
10090
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- Interactors 6
- Interactions 6
- Network