Mus musculus
TGFBR1
ALK5, AU017191, Alk-5, TbetaR-I, TbetaRI, RP23-457P12.1
transforming growth factor, beta receptor I
GO Process (54)
GO Function (14)
GO Component (9)
Gene Ontology Biological Process
- activation of MAPKK activity [ISO]
- angiogenesis [IMP]
- anterior/posterior pattern specification [IGI]
- artery morphogenesis [IMP]
- blastocyst development [IDA]
- cell motility [ISO]
- cellular response to transforming growth factor beta stimulus [IDA, ISO]
- collagen fibril organization [IMP]
- embryo development [IMP]
- embryonic cranial skeleton morphogenesis [IMP]
- endothelial cell migration [IMP]
- epithelial to mesenchymal transition [ISO]
- germ cell migration [IMP]
- heart development [IMP]
- in utero embryonic development [IMP]
- kidney development [IGI]
- lens development in camera-type eye [IMP]
- male gonad development [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of chondrocyte differentiation [IMP]
- negative regulation of endothelial cell differentiation [ISO]
- negative regulation of endothelial cell proliferation [IGI]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- neuron fate commitment [IMP]
- palate development [IGI, IMP]
- parathyroid gland development [IMP]
- pathway-restricted SMAD protein phosphorylation [ISO]
- peptidyl-serine phosphorylation [ISO]
- peptidyl-threonine phosphorylation [ISO]
- pharyngeal system development [IMP]
- positive regulation of SMAD protein import into nucleus [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cellular component movement [ISO]
- positive regulation of filopodium assembly [IMP]
- positive regulation of pathway-restricted SMAD protein phosphorylation [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- post-embryonic development [IMP]
- protein autophosphorylation [ISO]
- protein phosphorylation [IGI, ISO]
- regulation of gene expression [IMP]
- regulation of protein binding [IMP]
- regulation of protein ubiquitination [ISO]
- regulation of transcription, DNA-templated [ISO]
- response to cholesterol [IDA, ISO]
- response to estrogen [ISO]
- signal transduction [ISO]
- skeletal system development [IGI]
- skeletal system morphogenesis [IGI]
- thymus development [IMP]
- transforming growth factor beta receptor signaling pathway [IDA, IMP, ISO]
- transmembrane receptor protein serine/threonine kinase signaling pathway [IGI]
Gene Ontology Molecular Function- ATP binding [ISO]
- I-SMAD binding [ISO]
- SMAD binding [IDA, ISO]
- growth factor binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein heterodimerization activity [ISO]
- protein kinase activity [ISO]
- protein serine/threonine kinase activity [ISO]
- transforming growth factor beta binding [IPI, ISO]
- transforming growth factor beta receptor activity, type I [ISO]
- transforming growth factor beta-activated receptor activity [IDA, IGI, ISO]
- type II transforming growth factor beta receptor binding [ISO]
- ubiquitin protein ligase binding [ISO]
- ATP binding [ISO]
- I-SMAD binding [ISO]
- SMAD binding [IDA, ISO]
- growth factor binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein heterodimerization activity [ISO]
- protein kinase activity [ISO]
- protein serine/threonine kinase activity [ISO]
- transforming growth factor beta binding [IPI, ISO]
- transforming growth factor beta receptor activity, type I [ISO]
- transforming growth factor beta-activated receptor activity [IDA, IGI, ISO]
- type II transforming growth factor beta receptor binding [ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 28
- Interactions 36
- Network