Mus musculus
THBS1
TSP-1, TSP1, Thbs-1, tbsp1, RP23-234E8.1
thrombospondin 1
GO Process (55)
GO Function (12)
GO Component (11)
Gene Ontology Biological Process
- activation of MAPK activity [ISO]
- behavioral response to pain [IMP]
- blood vessel morphogenesis [IGI]
- cell cycle arrest [ISO]
- cell migration [ISO]
- cellular response to nitric oxide [IMP]
- endocardial cushion development [IGI]
- engulfment of apoptotic cell [ISO]
- growth plate cartilage development [IGI, IMP]
- inflammatory response [IMP]
- negative regulation of angiogenesis [IDA, IMP, ISO]
- negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of blood vessel endothelial cell migration [ISO]
- negative regulation of cGMP-mediated signaling [ISO]
- negative regulation of cell-matrix adhesion [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of dendritic cell antigen processing and presentation [ISO]
- negative regulation of endothelial cell chemotaxis [ISO]
- negative regulation of endothelial cell migration [ISO]
- negative regulation of endothelial cell proliferation [IMP, ISO]
- negative regulation of fibrinolysis [ISO]
- negative regulation of fibroblast growth factor receptor signaling pathway [ISO]
- negative regulation of interleukin-12 production [ISO]
- negative regulation of nitric oxide mediated signal transduction [ISO]
- negative regulation of plasma membrane long-chain fatty acid transport [ISO]
- negative regulation of plasminogen activation [ISO]
- outflow tract morphogenesis [IGI]
- peptide cross-linking [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of blood coagulation [ISO]
- positive regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell-substrate adhesion [IDA]
- positive regulation of chemotaxis [ISO]
- positive regulation of endothelial cell apoptotic process [ISO]
- positive regulation of endothelial cell migration [ISO]
- positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- positive regulation of fibroblast migration [ISO]
- positive regulation of macrophage activation [ISO]
- positive regulation of macrophage chemotaxis [IMP]
- positive regulation of phosphorylation [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of reactive oxygen species metabolic process [ISO]
- positive regulation of transforming growth factor beta production [ISO]
- positive regulation of transforming growth factor beta receptor signaling pathway [IMP, ISO]
- positive regulation of translation [ISO]
- positive regulation of tumor necrosis factor biosynthetic process [ISO]
- regulation of cGMP metabolic process [ISO]
- response to calcium ion [ISO]
- response to endoplasmic reticulum stress [IMP]
- response to glucose [ISO]
- response to magnesium ion [ISO]
- response to mechanical stimulus [ISO]
- sprouting angiogenesis [ISO]
Gene Ontology Molecular Function- collagen V binding [ISO]
- extracellular matrix binding [IDA]
- fibrinogen binding [ISO]
- fibroblast growth factor binding [ISO]
- fibronectin binding [ISO]
- heparin binding [ISO]
- integrin binding [ISO]
- laminin binding [ISO]
- low-density lipoprotein particle binding [ISO]
- phosphatidylserine binding [ISO]
- protein binding [IPI]
- transforming growth factor beta binding [ISO]
- collagen V binding [ISO]
- extracellular matrix binding [IDA]
- fibrinogen binding [ISO]
- fibroblast growth factor binding [ISO]
- fibronectin binding [ISO]
- heparin binding [ISO]
- integrin binding [ISO]
- laminin binding [ISO]
- low-density lipoprotein particle binding [ISO]
- phosphatidylserine binding [ISO]
- protein binding [IPI]
- transforming growth factor beta binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204175
10090
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- Interactors 14
- Interactions 15
- Network